宫颈上皮内瘤变与生殖道感染关系的临床分析

The clinical analyzing of cervical intraepithelial neoplasia and genital tract infection

目的探讨颈上皮内瘤变与生殖道感染关系情况。方法分析我院2015年2月~2017年4月就诊的70例宫颈上皮内瘤变患者临床资料,70例患者作为CIN组,选取同期非宫颈癌、非宫颈上皮内瘤变患者50例作为对照组。结果 CIN组HPV16/18、Uu、Ct、BV、滴虫阳性率均高于对照组,CIN组HPV16/18合并Ct阳性、BV阳性、滴虫阳性率均高于对照组,CIN组HPV16/18阴性合并Ct阴性、BV阴性、滴虫阴性比例均低于对照组,HPV16/18阳性率和Uu阳性、Ct阳性、BV阳性、滴虫阳性率均呈现明显正相关,差异有统计学意义(P<0.05)。结论 HPV16/18感染与Uu、Ct、BV、滴虫感染有一定的相关性,与CIN病变进展密切相关,临床上应注意监测。

Objective To approach cervical intraepithelial neoplasia and genital tract infection.Methods The 70 cases clinical data of cervical intraepithelial neoplasia patients in our hospital from 2015.2 to 2017.4 were analyzed,70 cases patients were CIN group,then the no cervical carcinoma,no cervical intraepithelial neoplasia of 50 cases patients were selected as control group.Results The positive rate of CIN group HPV16/18,Uu,Ct,BV、trichomonad were higher than control group,the HPV16/18 combined with Ct positive,BV positive,trichomonad positive of CIN group were higher than control group,the HPV16/18 negative combined with Ct negative,BV negative,trichomonad negative rate of CIN group were lower than control group,the positive rate of HPV16/18 and Uu positive,Ct positive,BV positive,trichomonad positive rate were significant positive correlation,(P<0.05),the difference were statistical significance.Conclusion The HPV16/18 infection and Uu,Ct,BV,trichomonad infection are relevance,which has closely associated with CIN lesions progress,which should attention monitoring.