钛涂层复合补片与普通聚丙烯补片在腹腔镜腹股沟疝修补术中效果的前瞻性随机对照研究

A prospective,randomized control study between titanium coating mesh and polypropylene mesh in laparoscopic inguinal hernia repair

目的对比分析钛涂层补片与普通聚丙烯平片在经腹腹腔镜腹股沟疝修补术中的应用价值。方法将2016年1月至6月间共48例行腹腔镜经腹疝修补术的患者纳入本研究,采用Microsoft Excel软件中的Randbetween函数产生随机编号随机将其中24例患者应用钛涂层补片作为观察组,24例应用普通聚丙烯平片作为对照组,对比两组患者手术时间、术中出血量、住院时间、住院费用、复工时间、术后合并症等指标。结果两组均顺利完成手术。两组患者手术时间、术中出血量、住院时间、复工时间差异均无统计学意义(P>0.05),住院费用、血清肿发生率和异物感的差异有统计学意义(P<0.05)。术后随访1年,两组病例均无术后复发、感染、慢性疼痛。观察组发生血清肿1例、异物感6例,对照组发生血清肿5例、异物感8例,观察组住院花费较对照组高(P<0.05)。结论应用钛涂层补片可减低术后血清肿和异物感的发生率,不会增加复发率,但住院花费可能相对较高,具有较高的临床应用价值。

Objective To compare the effect between Titanium coating mesh and polypropylene mesh in laparoscopic inguinal hernia repair.Methods A total of 48 patients performed laparoscopic inguinal hernia repair from Jan.2016 to Jun.2016 were included into this study.All patients were divided into two groups randomly,including Titanium coating mesh group(observation group,n=24)and polypropylene mesh group(control group,n=24).The operation time,intraoperative bleeding,hospital stay,hospital cost,time return to work and complications were analyzed.Results All of the operations were performed successfully.No statistical difference was observed of operation time,intraoperative bleeding,hospital stay,time return to work between two groups(P>0.05).The difference of hospital cost,incidence of seroma and foreign body sensation were statistically(P<0.05).No recurrence,infection or chronic pain was observed at 1 year follow-up.In observation group,1 seroma case and 6 foreign body sensation cases were observed.And in control group,5 seroma cases and 8 foreign body sensation cases were observed,with lower hospital cost(P<0.05).Conclusion Use of Titanium coating mesh may decrease the incidence of seroma and foreign body sensation with same risk of recurrence and complications.It is worthy to be used for clinical practice although hospital cost may be higher than polypropylene mesh.