类风湿关节炎患者病情有或无“活动后减轻”其中医证候异同的临床研究

Clinical Study of TCM Syndromes of Rheumatoid Arthritis Patients with or without "Relieving After Activity"

目的:探讨类风湿关节炎患者病情有或无"活动后减轻"其中医证候的异同。方法:将河南风湿病医院类风湿关节炎患者基线资料数据库(HFRA数据库)中收录的409例患者按病情有无活动后减轻分为活动后减轻组和无活动后减轻组。并采用SPSS 19.0软件分析2组在关节表现及关节外表现方面的区别与联系。结果:在一般资料中,无活动后减轻组家族史更明显,在病程、晨僵持续时间中,无活动后减轻组病程较长,活动后减轻组晨僵更明显。活动后减轻组气、血、阳虚等症较为明显,同时兼见气滞、血瘀;而无活动后减轻组风、寒、湿、热等实症为主,同时兼见气虚症。结论:活动后减轻组以虚症为主,无活动后减轻组以实症为主。

Objective:To explore the similarities and differences of TCM Syndromes of patients with rheumatoid arthritis with or without"relieving after activity".Methods:Four hundred and nine patients with rheumatoid arthritis in Henan Rheumatology Arthritis database(HFRA database)were divided into two groups according to whether they were relieved with or without activity:Group 1(with activity)and Group 2(without activity).Software SPSS 19.0 was used to analyze the differences and relations between the two groups in joint performance and extra-articular performance.Results:In general,Group 2 had a more obvious family history and a longer course of disease,while the duration of morning stiffness of Group 1 was more obvious.Deficiency of qi,blood and yang in Group 1 was more obvious,as well as qi stagnation and blood stasis.While Group 2 had sthenia syndromes such as wind,cold,dampness and heat,as well as qi deficiency.Conclusion:Group 1 mainly demonstrates as deficiency syndromes,while Group 2 mainly has sthenia syndromes with relatively.