前额叶损伤与视空间工作记忆的神经机制研究进展

Progress in the study of the neural mechanisms of prefrontal lobe damage and visual spatial working memory

视空间处理器是工作记忆的重要组成部分,主要用来存储视觉客体和空间信息,负责产生、操作和保持视觉映象,在行为和社会认知方面起着重要的作用。工作记忆最早是由英国心理学家Baddeley和Hitch于1974年提出的一个记忆模型,指一种对信息进行暂时性加工和存储的能量有限的记忆系统。额叶损伤成为临床上最为常见的脑叶损伤部位,各种类型的记忆功能障碍也成为临床上额叶损伤患者最常见的外伤后遗症。关于额叶损伤导致记忆功能障碍的发生机制和认知范式研究已成为国内外研究热点。

Visual spatial processor is an important part of working memory,is mainly used for the storage of visual object and spatial information,responsible for producing,operating and maintaining the visual image,which plays an important role in social cognition and behavior.Working memory is a memory model proposed by the British psychologist Baddeley and Hitch in 1974,which refers to a limited memory system for temporary processing and storage of information.Frontal lobe injury become the common position of brain injury in clinic and various types of memory dysfunction has also become the most common clinical patients with frontal lobe damage trauma sequela.The research on the mechanism of memory dysfunction and cognitive paradigm has become a hot research topic in the domestic and international.