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高频重复经颅磁刺激联合帕罗西汀治疗抑郁症的早期疗效 被引量:3

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摘要 目的:高频重复经颅磁刺激联合帕罗西汀治疗抑郁症的早期疗效。方法:将确诊的60例首发抑郁症,未系统用药或用药时间<5 d的病患,按照治疗方式的区别随机分为治疗组与对照组。治疗组给以高频重复经颅刺激(15Hz r TMS治疗)配合口服药物帕罗西汀(20 mg晨时口服),对照组予假高频重复经颅刺激联合口服药物帕罗西汀。两组均进行围期4周的治疗,治疗结束后将两组HAMD评分和MADS评分进行对比分析。结果:从HAMD评分评定疗效,治疗组总有效率为(93.33%),对照组为(73.33%),治疗组疗效明显优于对照组,两组对比具有统计学意义(P<0.05)。MADS评分上在治疗前(P>0.05)组间对比无统计学意义,治疗后1周、2周、4周治疗组疗效优于对照组,两组相比具有统计学意义(P<0.05)。结论:抑郁症患者通过高频重复经颅磁刺激联合帕罗西汀治疗效果比单纯口服抗抑郁药物帕罗西汀的早期疗效更为显著,值得临床推广。
作者 潘会敏
机构地区 许昌市建安医院
出处 《山西职工医学院学报》 CAS 2018年第1期61-63,共3页 Journal of Shanxi Medical College for Continuing Education
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  • 1Shajahan PM, Glabus MF, Steele JD, et al. Left dorso-lateral repetitive transcranial magnetic stimulation affects cortical excitability and functional connectivity, but does not impair cognition in major depression[ J]. Prog Neuropsychopharmacol Biol Psychiatry ,2002, 26 : 945 -954.
  • 2Zanardini R, Gazzoli A, Ventriglia M, et al. Effect of repetitive transcranial magnetic stimulation on serum brain derived neurotrophic factor in drug resistant depressed patients [ J ]. J Affect Disord, 2006,91:83-86.
  • 3Januel D, Dumortier G, Verdon CM, et al. A double-blind sham controlled study of right prefrontal repetitive transcranial magnetic stimulation (rTMS) : therapeutic and cognitive effect in medication free unipolar depression during 4 weeks [ J ]. Prog Neuropsychopharmacol Biol Psychiatry ,2006,30 : 126-130.
  • 4Jorge RE, Robinson RG, Tateno A, et al. Repetitive transcranial magnetic stimulation as treatment of poststroke depression:a preliminary study[ J]. Biol Psychiatry,2004,55:398-405.
  • 5Manes F, Jorge R, Morcuende M, et al. A controlled study of repetitive transcranial magnetic stimulation as a treatment of depression in the elderly [ J ]. Iat Psychogeriatry,2001, 13:225-231.
  • 6Rachid F, Bertschy G. Safety and efficacy of repetitive transcranial magnetic stimulation in the treatment of depression : a critical appraisal of the last 10 years [ J ]. Neurophysiology Clinique, 2006, 36 : 157-183.
  • 7Holtzheimer PE, Russo J, Avery DH. A meta-analysis of repetitive transcranial magnetic stimulation in the treatment of depression [ J ]. Psychopharmacol Bull,2001,35 : 149 -169.
  • 8Fregni F, Santos CM, Myzckowski ML, et al. Repetitive transcranial magnetic stimulation is as effective as fluoxetine in the treatment of depression in patients with Parkinson's disease[ J]. J Neurol Neumsurg Psychiatry,2004,75 : 1171-1174.
  • 9Janicak PC,, Dowd SM, Martis B, et al. Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for major depression : preliminary results of a randomized trial[J].Biol Psychiatry, 2002,51:659-667.
  • 10Pridmore S, Bruno R, Tumier-Shea Y, et al. Comparison of unlimited numbers of rapid transeranial magnetic stimulation (rTMS) and ECT treatment sessions in major depressive episode [ J ]. Int J Neuropsychopharmacol, 2000,3 : 129 -134.

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