新生儿PICC导管堵塞危险因素的多中心前瞻性研究

Risk factors of PICC related occlusion in neonate:aprospective multicenter study

目的探讨新生儿PICC导管堵塞的危险因素,为预防导管堵塞提供参考。方法对深圳市7所医院811例留置PICC导管的新生儿跟踪观察导管堵塞的发生情况,对影响导管堵塞的因素进行Logistic回归分析。结果共60例新生儿发生PICC导管堵塞,发生率7.4%(2.85/1 000导管日);Logistic回归分析结果显示,输液过程中使用精密过滤输液器是导管堵塞的保护因素(OR=0.113),导管留置时间>40d是危险因素(OR=2.780)。结论为避免新生儿PICC导管堵塞,输液过程中应使用精密过滤输液器,同时每天评估导管保留的必要性,尽早拔管。

Objective To explore the risk factors of PICC related occlusion in neonate,and to provide reference for preventing catheter occlusion.Methods A total of 811 neonates with PICC from 7 hospitals in Shenzhen city were followed up to observe the occurrence of catheter occlusion,and logistic regression analysis was used to analyze the factors affecting catheter occlusion.Results Totally 60 neonates suffered catheter occlusion,the incidence was 7.4%(2.85/1 000 catheter day).Logistic regression analysis showed that,usage of precision filtration infusion device was a protective factor(OR=0.113),while duration of indwelling catheter over 40 days was a risk factor(OR=2.780).Conclusion In order to avoid PICC related occlusion in neonate,a precise filtration infusion device should be used,and the necessity of catheter retention should be assessed everyday to extubate the catheter as early as possible.