肝脏容积加速采集序列增强扫描对颅内病变的应用价值

Application value of liver acquisition with volume acceleration sequence enhancement scanning in intracranial lesions

目的探讨肝脏容积加速采集(LAVA)序列增强扫描在颅内病变中的应用价值。方法分析40例颅内病变病人的头颅MRI增强检查影像,男19例,女21例,年龄12~80岁,平均(48.1±16.1)岁,均进行LAVA与快速反转恢复(FIR)T1WI序列两种增强扫描,测量两种序列获得影像的信噪比、对比噪声比、病变的面积,采用Wilcoxon符号秩检验进行比较。计算血管流动伪影出现率,观察病变的边界、信号,采用配对χ2检验进行比较。结果FIR T1WI与LAVA影像显示病变的边界、信号、面积差异无统计学意义(P>0.05),两者的信噪比、对比噪声比及血管流动伪影出现率分别为74.75(59.29~103.17)和26.72(22.61~34.78)、41.67(28.21~65.92)和22.89(14.76~32.27)、90%和27.5%,差异均有统计学意义(均P<0.001),扫描时间分别为195 s、87 s。LAVA序列检出6例肿瘤的供血动脉及引流静脉、3例静脉窦血栓、2例动脉瘤,FIR T1WI序列均未检出;7例转移瘤病人采用LAVA与FIR T1WI序列发现的病变数目分别为35个、30个。结论LAVA序列增强扫描可同时观察颅内病变和血管情况,与FIR T1WI对比扫描时间缩短,血管流动伪影出现率低,有较大的临床应用价值。

Objective To explore the application value of liver acquisition with volume acceleration(LAVA)sequence enhancement scanning in intracranial lesions.Methods A total of 40 patients with intracranial lesions underwent cranial enhanced MRI examination.Of the 40 patients,19 were male and 21 were female,and the mean age was 48.1±16.1 years old(ranging from 12-80 years old).Both LAVA and fast inversion recovery(FIR)T1WI sequence enhanced scanning were performed,followed by measurement of the signal-to-noise ratio(SNR),contrast to noise ratio(CNR)and area of the lesions on the two sequences.Group differences were evaluated with Wilcoxon signed rank test.The group comparison of incidence of vascular flow artifact,the lesion boundary and signal were assessed with pairedχ2 test.Results There were no significant difference in the lesion boundary,signal and area on FIR T1WI and LAVA(all P>0.05).The SNR,CNR and the incidence of vascular flow artifact of the two methods were 74.75(59.29~103.17)and 26.72(22.61~34.78),41.67(28.21~65.92)and 22.89(14.76~32.27),90%and 27.5%,respectively(all P<0.001).The scanning time was 195 s and 87 s,respectively.The feeding artery and draining vein in 6 cases,sinus thrombosis in 3 cases and aneurysm in 2 cases were detected with the LAVA sequence,whereas the lesions could not be detected on the FIR T1WI sequence.The numbers of lesions in 7 patients with metastases were 35 and 30,respectively,on the LAVA and FIR T1WI sequences.Conclusion The intracranial lesion and the blood vessels can be identified with LAVA sequence enhancement scanning which has shorter scanning time and lower occurrence rate of blood flow artifact compared with FIR T1WI sequence.LAVA sequence possesses greater clinical application value.