食管贲门癌术后胃排空障碍的影响因素

Influencing factors of delayed gastric emptying after esophageal and cardiac cancer surgery

目的探讨食管贲门癌术后胃排空障碍的相关因素及预防措施。方法 45例食管贲门癌术后胃排空障碍患者作为观察组,45例食管贲门癌术后无胃排空障碍患者作为对照组,比较2组患者相关因素的差异。结果单因素分析显示,年龄大、体质量指数高、教育时间短、营养不良、不良心理状态、居住地农村、手术切口大、术中失血量多、手术时间长、术后镇痛泵应用、补液量多等与胃排空障碍的发生均有相关性(P<0.05)。Logistic回归分析显示,胃排空障碍得独立影响因素有年龄大(OR=4.15,95%CI:1.89~26.30)、不良心理反应(OR=3.96,95%CI:1.38~25.38)、手术时间长(OR=3.40,95%CI:1.11~20.28)、营养不良(OR=3.02,95%CI:1.09~19.35)。结论胃排空障碍是食管贲门癌等手术常见的并发症之一,影响因素复杂。

Objective To investigate the related factors and preventive measures of delayed gastric emptying after operation for esophageal and cardiac carcinoma.Methods A total of 45 patients with delayed gastric emptying after operation for esophageal and cardiac carcinoma were selected as observation group,and 45 patients without delayed gastric emptying after operation for esophageal and cardiac carcinoma were selected as control group.Differences in the relevant factors were compared between the two groups.Results Single factor analysis showed that older age,high body mass index,short time education,malnutrition,poor mental state,rural residence,surgical incision,blood loss,long operation time,postoperative analgesia pump application,and the large amount of fluid volume were related risks of delayed gastric emptying(P<0.05).The Logistic regression analysis showed that older age(OR=4.15,95%CI:1.89~26.30),bad psychological reaction(OR=3.96,95%CI:1.38~25.38),long operation time(OR=3.40,95%CI:1.11~20.28)and malnutrition(OR=3.02,95%CI:1.09~19.35)were independent factors of delayed gastric emptying.Conclusion Delayed gastric emptying is one of the common complications after operation for esophageal and cardiac carcinoma,and the influencing factors are complex.