25(OH)D水平与产妇产后出血的相关性探究

Study on Correlation between the 25(OH)D Level and Postpartum Hemorrhage of Delivery Women

目的探讨25(OH)D水平与产妇产后出血的相关性探究。方法收集2014年2月—2017年2月来该院进行孕检并分娩的产妇2 433例,利用ELISA试剂盒检测患者血清25(OH)D浓度,利用Logistic分析25(OH)D水平与产妇产后出血相关性。结果 25(OH)D水平缺乏时,产妇产后出血发生概率为4.10%,25(OH)D水平不足时,产妇产后出血发生概率为1.39%,25(OH)D水平充足时,产妇产后出血发生概率为0.47%,25(OH)D不同水平与产妇产后出血发生概率经比较差异有统计学意义(P<0.05);对未发生产后出血和发生产后出血的两组患者进行Logistic回归分析,25(OH)D最大似然估计值和OR值均<0,即25(OH)D水平与产后出血的发生呈负相关性。结论维生素D不足或缺乏与产后出血的发生存在负相关性,增加产妇产后出血的风险。

Objective To study the correlation between the 25(OH)D level and postpartum hemorrhage of delivery women.Methods 2 433 cases of delivery women in our hospital for pregnant examination and delivery from February 2014 to February 2017 were selected and the serum 25(OH)D concentration of patients was tested by the ELISA kit,and the correlation between the 25(OH)D level and postpartum hemorrhage of delivery women was analyzed.Results The incidence rates of postpartum hemorrhage of delivery women were respectively 4.10%,1.39%,0.47%when the 5(OH)D level was lack,insufficient and sufficient,and the difference was statistically significant(P<0.05),and the Logistic regression analysis of patients with postpartum hemorrhage and patients without postpartum hemorrhage showed that the maximum likelihood estimator and OR value of 25(OH)D<0,namely 25(OH)D level was negatively correlated with the occurrence of postpartum hemorrhage.Conclusion The insufficient vitamin D or lack of vitamin D are negatively correlated with the occurrence of occurrence of postpartum hemorrhage and increase the risk of postpartum hemorrhage of delivery women.