替格瑞洛与氯吡格雷治疗在冠心病患者中的应用及效果对比分析

Analysis of Comparison and Application Effect of Ticagrelor and Clopidogrel in Treatment of Patients with Coronary Heart Disease

目的对比分析替格瑞洛与氯吡格雷治疗在冠心病患者中的应用及效果。方法将2014年1月—2017年1月该院收治的冠心病患者105例为研究对象,数字法分为两组,氯吡格雷组55例,替格瑞洛组50例,比较两组患者的治疗情况。结果替格瑞洛组患者的MACE总发生率(6.0%)低于氯吡格雷组(20.0%),两组之间比较差异有统计学意义(P<0.05)。结论在冠心病治疗中,替格瑞洛组MACE发生率、出血率和不良反应发生率低,应用效果显著。

Objective To compare and analyze the application effect of ticagrelor and clopidogrel in treatment of patients with coronary heart disease.Methods 105 cases of patients with coronary heart disease admitted and treated in our hospital from January 2014 to January 2017 were selected and randomly divided into two groups,including 55 cases in the ticagrelor group and 50 cases in the clopidogrel group,and the treatment situation was compared between the two groups.Results The total incidence rate of MACE in the ticagrelor group was lower than that in the clopidogrel group(6.0%vs 20.0%),and the difference was statistically significant(P<0.05).Conclusion The incidence rate of MACE,hemorrhage rate and incidence rate of adverse reactions of ticagrelor in treatment of patients with coronary heart disease are lower,and the application effect is obvious.