冰冻病理检查在甲状腺微小乳头状癌临床诊断中的应用价值

Clinical Value of Frozen Pathological Examination in the Diagnosis of Small Papillary Thyroid Carcinoma

目的探讨在甲状腺微小乳头状癌临床诊断中,冰冻病理检查的诊断价值。方法选取该院2016年1月—2017年7月42例术中冰冻甲状腺微小乳头状癌标本,对其术中获取的病理行常规石蜡切片和冰冻切片处理,并对其形态特征进行观察,以此作为判断依据。结果 33例确诊,31例浸润行为,28例见间质硬化,26例乳头结构,均能够观察到有核沟、核异型以及核内假包涵体;7例未诊断或者冰冻病理诊可疑,2例冰冻病理无病灶。结论在甲状腺微小乳头状癌临床诊断中,术中冰冻病理是一种具有较高应用价值的诊断方法,其具有诊断速度快,诊断准确高的特点,但在诊断中应当注意相关特征,同时通过细致的观察来实现对误诊、漏诊的控制,更好的提升诊断准确性。

Objective This paper tries to investigate the value of frozen pathological examination in the diagnosis of papillary thyroid microcarcinoma.Methods 42 cases of intraoperative frozen specimens of papillary thyroid microcarcinoma from January 2016 to July 2017 were selected,the pathological paraffin section and the frozen section treatment were implemented during the intraoperation,and their morphological characteristics were observed and which was taken as a judgment basis.Results 33 cases were diagnosed,31 cases of invasive behavior,28 cases showed interstitial sclerosis,26 cases of papillary structure,were able to have nuclear groove,nuclear atypia and nuclear package;7 cases were not diagnosed or suspected frozen pathology;pathologic diagnosis in 2 cases of pathological frozen lesions.Conclusion In the clinical diagnosis of papillary thyroid carcinoma,intraoperative frozen pathology is a valuable diagnostic method,which has the characteristics of fast diagnostic speed,high diagnostic accuracy,but the relevant characteristics should be paid attention to in the diagnosis of it,at the same time,through careful observation,the misdiagnosis and missed diagnosis can be controlled.The diagnostic accuracy can be better enhanced.