心脉隆治疗慢性心力衰竭的临床疗效探讨

Study on Clinical Curative Effect of Xinmailong in Treatment of Chronic Heart Failure

目的探讨采用心脉隆注射液治疗慢性心力衰竭的应用效果。方法该研究以该院在2016年2月—2017年4月期间的117例慢性心力衰竭患者为研究对象,并将其随机分为观察组(59例)和对照组(58例),其中对照组采取常规的慢性心力衰竭的治疗方式,而观察组在常规治疗方式的基础上加用心脉隆注射液,再比较分析两组的临床疗效。结果观察组的总有效率高于对照组,观察组在加用心脉隆注射液治疗后左室射血分数(45.15±5.15)%、N端B型脑钠肽前体(2 331.41±1 095.42)ng/L、最大代谢当量(34.15±5.78);对照组治疗后左室射血分数(38.42±4.62)%、N端B型脑钠肽前体(2 937.13±892.45)ng/L。差异有统计学意义(P<0.05)。结论心脉隆注射液对CHF有一定干预作用,可改善CHF患者临床症状及LVEF、NT—pro BNP、最大代谢当量,安全性比较好。

Objective To study the application effect of xinmailong in treatment of chronic heart failure.Methods 117 cases of patients with chronic heart failure in our hospital from February 2016 to April 2017 were selected as the research objects and randomly divided into two groups,the control group with 58 cases adopted the routine chronic heart failure treatment method,while the observation group with 59 cases adopted the xinmailong injection on the basis of the control group,and the clinical curative effect was compared and analyzed.Results The total effective rate in the observation group was higher than that in the control group,and the left ventricular ejection fraction,n-terminal pro-b-type natriuretic peptide,maximum metabolic equivalent in the observation group were respectively(45.15±5.15)%,(2 331.41±1 095.42)ng/L and the left ventricular ejection fraction,the biggest metabolic equivalent were(34.15±5.78).and n-terminal pro-b-type natriuretic peptide,in the control group after treatment were respectively(38.42±4.62)%and(2 937.13±892.45)ng/L(P<0.05),and the differences were statistically significant.Conclusion The xinmailong injection has a certain intervention effect on the CHF,which can improve the clinical symptoms,LVEF,NT-proBNP and maximum metabolic equivalent of CHF patients,and the safety is good.