不同级别慢性阻塞性肺疾病患者肺容量和弥散功能的特点及临床意义

Features and Clinical Significance of Lung Volume and Pulmonary Diffusion Function of Patients of Different Grades of Chronic Obstructive Pulmonary Diseases

目的探讨不同级别慢性阻塞性肺疾病患者肺容量和弥散功能的特点及临床意义。方法随机选取该院2016年3月—2017年4月收治的60例慢性阻塞性肺疾病患者,依据肺功能评价指标分为1级组11例(FEV1%≥80%)、2级组13例(50%≤FEV1%<80%)、3级组20例(30%≤FEV1%<50%)和4级组16例(FEV1%<30%)。对4组患者进行肺容量及弥散功能检测。观察对比4组患者肺功能及弥散功能差异、临床指标持续时间。结果 1级组FEV1(94.23±10.46)%、PEF(80.36±21.47)%、MMEF(37.98±9.89)%、RV(127.59±36.47)%、TLC(111.38±15.47)%;2级组FEV1(69.23±9.46)%、PEF(54.34±20.47)%、MMEF(26.98±9.18)%、RV(159.59±30.47)%、TLC(119.39±15.88)%;4级组FEV1(24.23±7.18)%、PEF(29.89±10.41)%、MMEF(7.91±9.89)%、RV(227.59±36.18)%、TLC(136.82±102.36)%,1级组肺容量和弥散功能指标优于2级组优于3级组优于4级组(P<0.05)。临床指标持续时间为:4级组>3级组>2级组>1级组(P<0.05)。结论随着病情的发展慢性阻塞性肺疾病患者肺容量会持续增加,肺弥散功能减弱,肺功能减退,慢性阻塞性肺疾病患者肺容量指标及弥散功能指标可作为诊断慢性阻塞性肺疾病的诊断标准之一。

Objective To study the features and clinical significance of lung volume and pulmonary diffusion function?of patients of different grades of chronic obstructive pulmonary diseases.Methods 60 cases of patients with chronic obstructive pulmonary disease admitted and treated in our hospital from March 2016 to April 2017 were randomly selected and divided into the level 1 group with 11 cases(FEV1%≥80%),level 2 group with 13 cases(50%≤FEV1%<80%),level 3 group with 20 cases(30%≤FEV1%<50%)and level 4 group with 16 cases(FEV1%<30%),and the lung volume and?pulmonary diffusion function of the four groups were tested,and the differences in the lung volume and pulmonary diffusion function and clinical index duration of the four groups were observed and compared.Results The FEV1,PEF,MMEF,RV,TLC in the level 1 group were respectively(94.23±10.46)%,(80.36±21.47)%,(37.98±9.89)%,(127.59±36.47)%,(111.38±15.47)%,and the FEV1,PEF,MMEF,RV,TLC in the level 2 group were respectively(69.23±9.46)%,(54.34±20.47)%,(26.98±9.18)%,(159.59±30.47)%,(119.39±15.88)%,and the FEV1,PEF,MMEF,RV,TLC in the level 4 group were respectively(24.23±7.18)%,(29.89±10.41)%,(7.91±9.89)%,(227.59±36.18)%,(136.82±102.36)%,and the lung volume and pulmonary diffusion function indexes:the level 1 group>the level 2 group>the level 3 group>the level 4 group(P<0.05),the clinical index duration:the level 4 group>the level 3 group>the level 2 group>the level 1 group(P<0.05).Conclusion With the development of the disease,the lung volume of patients with chronic obstructive pulmonary disease can continuously increases and the pulmonary diffusion function and pulmonary function decrease,and the lung volume and?pulmonary diffusion function of patients with chronic obstructive pulmonary diseases can be used as one of the diagnosis standards of chronic obstructive pulmonary disease.