尼可地尔和卡维地洛联合治疗64例冠心病心肌缺血的疗效

Therapeutic effect of nicorandil and carvedilol on 64 cases of myocardial ischemia with coronary heart disease

目的探讨尼可地尔和卡维地洛联合治疗冠心病心肌缺血的临床疗效。方法在我院2015年1月至2016年4月诊治的冠心病心肌缺血患者中抽取128例作研究对象,并依照随机抽签方式分为对照组(n=64,常规治疗)和研究组(n=64,应用尼可地尔和卡维地洛联合治疗),比较两组的治疗效果。结果研究组患者整体治疗有效率是96.88%,同对照组的85.94%比较,明显更高(P<0.05)。治疗后,两组的心肌缺血总负荷降低,心肌缺血阈功率升高,体力负荷时间延长,且研究组的上述指标均明显优于对照组(P<0.05)。结论尼可地尔和卡维地洛联合治疗冠心病心肌缺血的临床疗效突出,可推广应用。

Objective To explore the clinical effect of nicorandil and carvedilol on myocardial ischemia with coronary heart disease.Methods From January 2015 to April 2016,128 cases of patients with coronary heart disease treated in our hospital were selected as the study objects,and randomly divided into control group(n=64)which receiving conventional therapy and study group(n=64)which accepting the combination therapy of nicorandil and carvedilol.The treatment effects of the two groups were compared.Results The overall effective rate of the study group was 96.88%,which was significantly higher than 85.94%of the control group(P<0.05).After treatment,the total ischemia burden in both groups decreased,the threshold power of myocardial ischemia increased,and the physical load time prolonged;the above indexes in the study group were significantly better than those in the control group(P<0.05).Conclusion Nicorandil and carvedilol combination therapy has obvious effect in the treatment of coronary heart disease,which can be extended and applied.