心房颤动相关脑卒中60例临床治疗研究

Research on Clinical Treatment of 60 Cases with Auricular Fibrillation Related Stroke

目的对60例心房颤动相关脑卒中患者的临床治疗进行研究分析。方法将2015年4月—2017年5月在该院接受诊治的60例心房颤动相关脑卒中患者作为该次研究的主要对象,作为脑卒中组,另外选取60例心房颤动非脑卒中患者作为非脑卒中组,对两组患者的基础信息进行收集,观察两组患者的临床表现,同时对两组患者进行经胸超生心电图和头颅CT检查,对两组患者的各项资料进行对比分析,并对患者年龄、房颤类型及左房大小、并发症和预防性抗凝血治疗与脑卒中的关系进行研究分析。结果脑卒中组当中持续性房颤患者人数为53例(88.33%),51例患者左心房扩大,占比85.00%,而非脑卒中组当中持续性房颤患者人数仅为35例(58.33%),18例(30.00%)患者左心房扩大。脑卒中组当中高血压患者人数为27例(45.00%),而非脑卒中组当中高血压患者人数为20例(33.33%),另外脑卒中组当中患者合并糖尿病、血脂异常、心力衰竭的人数分别为11例、9例、3例,非脑卒中组当中患者合并糖尿病、血脂异常、心力衰竭的人数分别为4例、8例、7例。脑卒中组当中有5例患者服用阿司匹林进行治疗,剂量为75~100 mg/d,而非脑卒中组当中有16例患者服用阿司匹林进行治疗,剂量为75~300 mg/d,另外有2例患者采用华法林进行治疗。数据经检验差异有统计学意义(P<0.05)。结论糖尿病、血脂异常等疾病是影响心房颤动患者脑卒中发生的危险因素,采用合理的抗凝血、抗血小板药物进行治疗,对预防心房颤动患者发生脑卒中具有积极影响。

Objective To research and analyze the clinical treatment of 60 cases with auricular fibrillation related stroke.Methods 60 cases of patients with auricular fibrillation related stroke diagnosed in our hospital from April 2015 to May 2017 were selected as the stroke group,while 60 cases of patients with auricular fibrillation non-stroke were selected as the non-stroke group,and the basic information of the two groups was collected,and the clinical manifestations,transthoracic electrocardiogram and head CT examination,and various data were compared between the two groups,and the correlation between the age,fibrillation type,left atrium size,complications and predictive anticoagulation and stroke was researched and analyzed.Results In the stroke group,there were 53 cases with persistent atrial fibrillation(88.33%),and 51 cases with left atrial dilatation 85.00%,while in the non-stroke group,there were 35 cases with persistent atrial fibrillation(58.33%)and 18 cases with left atrial dilatation 30.00%,and in the stroke group,there were 27 hypertension cases 45.00%,while in the non-stroke group,there were 20 cases of hypertension patients(33.33%),and in the non-stroke group,there were respectively 4 cases,8 cases and 7 cases combined with diabetes,dyslipidemia and heart failure,and in the stroke group,there were 5 cases taking aspirin for treatment,with the dosage of 75~100 mg/d,and in the non-stroke group,there were 16 cases taking aspirin for treatment,with the dosage of 75~300 mg/d,besides,there were 2 cases taking warfarin for treatment,and the difference was statistically significant(P<0.05).Conclusion The diabetes and dyslipidemia are the risk factors of stroke of patients with auricular fibrillation,and the rational treatment of anticoagulation and antiplatelet drugs treatment has a positive effect on preventing the stroke of patients with auricular fibrillation.