调强配合后装放射治疗中晚期宫颈癌的效果研究

Research on Effect of Intensity-modulated Radiation Therapy in Treatment of Advanced Cervical Cancer

目的探究中晚期宫颈癌患者接受调强配合后装照射治疗的价值。方法选取2012年1月—2015年7月30例该院妇科收治的中晚期宫颈癌患者60例为该研究对象,根据其治疗措施不同分组,实验组30例实施调强配合后装照射治疗,对照组30例则实施二维普通照射与后装结合治疗,对比2组疗效、急性不良反应和远期不良反应的差异性。结果实验组总有效率(83.33%)明显高于对照组的总有效率(60.00%)(P=0.045,χ~2=4.021 9);实验组急性不良反应(放射性膀胱炎几率16.67%、肠炎几率33.33%、皮炎几率36.67%、骨髓抑制几率20.00%)几率、远期不良反应(慢性消化道症状几率16.67%、泌尿系统症状几率10.00%)几率均明显低于对照组(P<0.05)。结论中晚期宫颈癌患者接受调强配合后装照射治疗安全有效。

Objective To study the value of intensity-modulated radiation therapy in treatment of advanced cervical cancer.Methods 60 cases of patients with advanced cervical cancer treated in our hospital from January 2012 to July 2015 were selected and divided into two groups according to different treatment measures,with 30 cases in each,the experimental group used the intensity-modulated radiation therapy,while the control group used the two dimensional common radiation and modulated therapy,and the curative effect,acute toxic and side reactions and long-term and toxic and side reactions were compared between the two groups.Results The total effective rate in the experimental group was obviously higher than that in the control group(83.33%vs 60.00%)(P=0.045,χ2=4.0219),and the occurrence probabilities of acute toxic and side reactions(radiocystitis 16.67%,enteritis 33.33%,dermatitis 36.67%,bone marrow depression 20.00%)and long-term and toxic and side reactions(chronic digestive tract symptom 16.67%and urinary system symptoms 10.00%)were obviously lower than those in the control group(P<0.05).Conclusion The intensity-modulated radiation therapy in treatment of advanced cervical cancer is safe and effective.