手术一期切除治疗结肠癌致急性肠梗阻的临床效果

Clinical effect of one-stage resection in the treatment of acute intestinal obstruction caused by colon cancer

目的探究手术一期切除治疗结肠癌致急性肠梗阻的临床效果。方法选取2011年1月~2015年1月我院收治的66例结肠癌致急性肠梗阻患者,采用随机数字表法将其分为观察组、对照组,每组33例。比较两组的治疗效果,实验室检查指标、并发症发生率。结果观察组的治疗总有效率显著高于对照组,差异有统计学意义(P<0.05);两组患者治疗前的相关实验室检查数据比较,差异无统计学意义(P>0.05);观察组治疗后的血pH值、尿pH值、甲酸根(HCO2)显著高于对照组,差异有统计学意义(P<0.05),观察组的血清K+、癌胚抗原(CEA)、白细胞计数(WBC)显著低于对照组,差异有统计学意义(P<0.05);观察组并发症发生率显著低于对照组,差异有统计学意义(P<0.05)。结论将一期手术切除早期应用于结肠癌致急性肠梗阻患者后,患者血pH值、尿pH值、HCO2上升,血清K+、CEA、WBC下降,治疗效果显著,且并发症发生率显著降低,此方法值得应用与推广。

Objective To explore the clinical effect of one-stage resection in the treatment of acute intestinal obstruction caused by colon cancer.Methods From January 2011 to January 2015,66 patients with acute intestinal obstruction caused by colon cancer were selected and randomly divided into observation group and control group,33 cases in each group.The therapeutic effect,laboratory examination index and complication rate were compared between the two groups.Results The total effective rate of the observation group was significantly higher than that of the control group(P<0.05).There was no significant difference between the two groups(P>0.05).The blood pH value,urinary pH value and formate(HCO2)in the observation group were significantly higher than those in the control group(P<0.05).The serum K+,carcinoembryonic antigen(CEA)and leukocyte count(WBC)in the observation group were significantly lower than those in the control group(P<0.05).The incidence of complications in the observation group was significantly lower than that in the control group(P<0.05).Conclusion For patients with acute intestinal obstruction caused by colon cancer,the early one-stage resection can increase the index of blood pH value,urinary pH value and HCO2,reduce the serum K+,CEA and WBC as well as incidence rate of complications.This method is worthy of application and popularization.