补肾活血中药治疗骨质增生继发性腰痛的效果及对患者骨硬化素蛋白水平的影响

Effect of Bushen Huoxue traditional Chinese medicine in the treatment of hyperosteogeny secondary low back pain and influence on bone sclerosis protein level of patients

目的探讨补肾活血中药治疗骨质增生继发性腰痛的效果及对患者骨硬化素蛋白(SOST)水平的影响。方法随机选取2015年5月~2017年5月我站接诊治疗的骨质增生继发性腰痛患者80例,依据治疗方法将患者分为单纯西医组(n=40)和西医结合补肾活血中药组(中西医结合组,n=40)。比较两组患者的中医症候积分、临床疗效、SOST水平。结果中西医结合组患者的关节及肌肉疼痛、腰膝酸软、屈伸不利、畏寒肢冷、脉沉细弱或细数、苔薄白或少津积分均显著低于单独西医组(P<0.05),总有效率(90.0%)显著高于单独西医组的70.0%(P<0.05),SOST水平显著高于单独西医组(P<0.05)。结论补肾活血中药治疗骨质增生继发性腰痛的效果显著,能够有效提升患者的SOST水平。

Objective To investigate the effect of Bushen Huoxue traditional Chinese medicine in the treatment of hyperosteogeny secondary low back pain and influence on bone sclerosis protein(SOST)level of patients.Methods Eighty cases of patients with hyperosteogeny secondary low back pain from May 2015 to May 2017 treated in our station were randomly selected,and patients were divided into the single Western Medicine group(n=40)and Western Medicine combined with Chinese herbal group(combination of Traditional Chinese and Western Medicine group,n=40)according to the treatment methods.TCM syndrome score,clinical effect and SOST level were compared in patients between the two groups were compared.Results The score of joint and muscle pain,soreness and weakness of waist and knees,unfavourable flexion and extension,intolerance to cold and cold limbs,weak or breakdowning pulse,thin white or atrazine coating on the tongue in patients of combination of Traditional Chinese and Western Medicine group were significantly lower than those of single Western Medicine group(P<0.05),and the total effective rate(90.0%)was significantly higher than that of the Western Medicine group(40.0%)(P<0.05),and the level of SOST was significantly higher than that of the single Western Medicine group(P<0.05).Conclusion The effect of Bushen Huoxue traditional Chinese medicine in the treatment of hyperosteogeny secondary low back pain is significant,and it can effectively raise the SOST level of patients.