滇黔桂三省交界区脑囊虫病采用大剂量吡喹酮抗囊虫治疗的疗效

Effect of large dose praziquantel in the treatment of cerebral cysticercosis at the junction of the Dianqiangui provinces

目的:探讨大剂量吡喹酮治疗脑囊虫病的效果。方法:对滇黔桂三省交界区55例脑囊虫病患者(观察组)采用大剂量吡喹酮抗囊虫治疗,对同时期53例患者(对照组)采用常规剂量吡喹酮抗囊虫治疗,比较两组治疗效果及并发症发生率。结果:观察组治疗有效率为92.7%,高于对照组的84.9%(P<0.05);观察组并发症发生率为5.5%,对照组并发症发生率为3.7%,组间比较差异无统计学意义(P>0.05)。结论:采用大剂量吡喹酮抗囊虫治疗能够提高对脑囊虫病的治疗有效率,且用药方案不会增加患者的并发症发生率。

Objective:To investigate the effect of large dose praziquantel in the treatment of cerebral cysticercosis.Methods:55 cases of patients with cerebral cysticercosis at the junction of the Dianqiangui provinces(the observation group)were treated with high dose praziquantel treatment,and 53 patients at the same period(control group)were treated with routine dose of praziquantel.The treatment effect and complication incidence rate between the two groups were compared.Results:The effective rate of the observation group was 92.7%,which was higher than that of the control group(84.9%)(P<0.05).The complication incidence rate in the observation group was 5.5%,and the complication incidence rate in the control group was 3.7%;there was no significant difference between the two groups(P>0.05).Conclusion:The large dose of praziquantel treatment can improve the treatment efficiency of cerebral cysticercosis,and the medication does not increase the incidence of complications in patients.