用重建心阻抗图测量心脏效率和内功的初步研究

Initial Studies on Measurement of Cardiac Efficiency and Internal Work with Reconstructed Impedance Cardiogram

目的探讨无损伤测量心脏效率和内功的方法。方法基于生理学的相关资料和大量测量数据的统计分析,提出测量心脏效率和内功的计算方法,测量180例健康成人志愿者和181例心血管患者(高血压病患者51例,冠心病患者58例,心功能不全患者72例)的重建心阻抗图,用其相关波形参数计算心脏效率、内功、心输出量等,利用统计软件SPSS12.0完成统计分析。结果180例健康志愿者的心脏效率和内功分别为(22.7±2.0)%和(242.6±62.2)J·min^(-1);心脏效率随年龄的增大而减小,内功则随年龄增大而增大,且青年组与老年组之间有显著性差异[(218.8±45.1)J·min^(-1)比(266.9±66.4)J·min^(-1),P<0.01];男性组和女性组心脏效率比较差异无统计学意义(P>0.05),男性组的内功显著大于女性组(P<0.01)。高血压病、冠心病、心功能不全患者的心脏效率分别为(16.9±2.7)%、(19.1±2.4)%、(17.2±3.2)%,均显著小于老年组(P<0.001)。结论本文测量心脏效率和内功的方法是可行的。

Objective To investigate the noninvasive method for measuring the cardiac efficiency and internal work.Methods The computed method for measuring the cardiac efficiency and internal work was suggested on the basis of physiological data and statistical data analysis.The reconstructed impedance cardiograms were measured in l80 normal adults and 181 patients with cardiovascular disease(51 patients with hypertension,58 patients with coronary heart disease and 72 patients with cardiac insufficiency).Cardiac efficiency,internal work and cardiac output were calculated using the relative waveform parameters.The statistical analysis was performed using the SPSS12.0 software.Results The cardiac efficiency and internal work were(22.7±2.0)%and(242.6±62.2)J·min-1 in the 180 normal adults,respectively.The cardiac efficiency decreased and the internal work increased with the age.There was a notable difference in internal work between youth group[(218.8±45.1)J·min-1]and elderly group[(266.9±66.4)J·min-1](P<0.01).No significant difference in cardiac efficiency was found between male group and female group(P>0.05).However,the internal work in male group was obviously greater than that in female group(P<0.01).The cardiac efficiencies in patients with hypertension coronary,patients with heart disease and patients with cardiac insufficiency were,respectively(16.9±2.7)%,(19.1±2.4)%and(17.2±3.2)%,markedly lower than those in elderly group(P<0.001).Conclusion The method suggested in this paper is feasible for measuring cardiac efficiency and internal work.