血锂浓度监测在治疗精神疾病中的应用价值

Analysis of the Value of Serum Concentration of Lithium Monitoring in the Treatment of Psychosis Diseases

目的探讨血锂浓度监测在精神疾病中的效果。方法回顾性总结我院2016年4月—2017年4月精神科收治的93例长时间服用碳酸锂的患者的临床资料,所有患者均使用IMS-972Plus电解质分析仪检测血锂浓度。结果 93例患者,其中18例(19.35%)血锂浓度<0.50mmol/L表明未至治疗浓度,73例(78.49%)为0.50~1.40 mmol/L表明已至治疗浓度,2例(2.15%)>1.40 mmol/L表明伴早期中毒表现。结论血锂浓度监测不仅有利于指导临床用药,同时还可避免中毒的出现。

Objective To investigate the effect of serum concentration of lithium monitoring in the treatment of psychosis diseases.Methods The clinical data of 93 patients from April 2016 to April 2017 who took lithium carbonate for a long time in our hospital were retrospectively reviewed.All patients were tested by IMS-972Plus electrolyte analyzer.Results 93 patients,including 18 cases(19.35%)of the blood lithium concentration<0.50 mmol/L,and showed that the concentration was not reached,73 patients(78.49%)were 0.50~1.40 mmol/L indicating that the treatment concentration has been reached,2 cases(2.15%)>1.40 mmol/L showed that with early manifestations of poisoning.Conclusion The monitoring of Serum concentration of lithium is not only helpful to guide clinical medication,but also to avoid the occurrence of poisoning,is worth popularizing and applying.