结核性、恶性胸腔积液的鉴别诊断的研究进展

Progress in the Differential Diagnosis of Tuberculous and Malignant Pleural Effusions

胸腔积液是临床常见的胸膜病变,也是多种疾病的伴随表现。据统计有50多种疾病可直接或间接引起胸腔积液。胸腔积液的病因诊断一直是临床上非常重视的话题,而结核性胸腔积液(TPE)和恶性胸腔积液(MPE)在呼吸内科最为常见,两种疾病的治疗完全不同,故早期诊断及合理治疗对患者的预后起着至关重要的作用。目前临床上有多种实验室指标及检测方法用于两种胸腔积液的鉴别,但各有利弊。随着实验技术及分子生物学的飞速发展,一些新的实验技术及实验指标应运而生。本文旨在对不同实验指标和检测方法对结核性、恶性胸腔积液的鉴别诊断价值进行综述。

Pleural effusion is a common clinical pleural disease,but also accompanied by a variety of diseases.According to statistics,more than 50 kinds of diseases can directly or indirectly cause pleural effusion.The etiological diagnosis of pleural effusion is clinically very important topic,and tuberculous pleural effusion(TPE)and malignant pleural effusion(MPE)is the most common respiratory medicine,the treatment of two diseases are completely different,so early diagnosis and reasonable treatment play a crucial role in the prognosis of patients.Currently there are a variety of clinical laboratory indicators and detection methods for the identification of two pleural effusion,but each has advantages and disadvantages.With the rapid development of experimental technology and molecular biology,some new experimental techniques and experimental indicators came into being.This article aims to summarize the differential diagnostic value of different experimental indicators and detection methods for tuberculous and malignant pleural effusion.