冠状动脉介入治疗前后C反应蛋白的变化及中西医结合治疗对其影响的观察

Changes of C Reactive Protein Before and After Coronary Intervention and the Effect of Integrated Traditional Chinese and Western Medicine on it

目的探讨利用冠状动脉介入治疗冠心病患者前后其C反应蛋白的变化情况,并分析采取中西医结合治疗对冠状动脉介入术后C反应蛋白的影响。方法选择2016年11月—2017年11月本院收治的60例行冠状动脉介入术的冠心病患者作为研究对象,按照患者入院顺序将其分为两组,治疗组与对照组各30例。其中治疗组采取中西医结合治疗方式,对照组实施西医治疗,比较两组患者在手术治疗前后其C反应蛋白的变化情况。结果两组患者介入术后4 h的血浆C反应蛋白值高于术前,差异具有统计学意义(P<0.05),两组患者术后15 d血浆C反应蛋白值明显低于术后4 h,差异具有统计学意义(P<0.05)。介入治疗前后两组患者C反应蛋白值差异无统计学意义(P>0.05)。两组患者临床治疗效果差异无统计学意义(P>0.05)。结论采取中西医结合治疗能够显著地降低冠状动脉介入术后C反应蛋白值的升高,但与单纯西医治疗相比,中西医结合治疗并未显著增加临床疗效。

Objective To explore the changes of C reactive protein in patients with coronary artery disease before and after coronary artery intervention,and to analyze the effect of combination of traditional Chinese and Western Medicine on C reactive protein after coronary intervention.Methods 60 cases of coronary artery disease treated in our hospital from November 2016 to November 2017 were selected as the subjects.According to the order of admission,the patients were divided into two groups,the treatment group and the control group with 30 cases in each group.The treatment group was treated with integrated traditional Chinese and Western medicine,and the control group was treated with western medicine,and the changes of C reaction protein in the two groups were compared before and after the operation.Results The value of plasma C reactive protein in the two groups of two groups after intervention was higher than that before operation,the difference was statistically significant(P<0.05).The value of C reaction protein in the two groups after operation was significantly lower than 4 h after operation(P<0.05).There was no significant difference in C reactive protein between the two groups before and after interventional treatment(P>0.05).There was no significant difference in the clinical efficacy between the two groups(P>0.05).Conclusion The combination of traditional Chinese and Western medicine can significantly reduce the increase of C reaction protein value after coronary intervention,but compared with the simple western medicine treatment,the combination of traditional Chinese and Western medicine does not significantly increase the clinical effect.