鲍曼不动杆菌基因分型技术的研究进展

Research progress on genotyping techniques of Acinetobacter baumannii

鲍曼不动杆菌为非发酵糖类革兰阴性杆菌,具有强大的获得耐药性和克隆传播的能力,广泛分布于医院环境,是医院内感染的重要病原菌之一。因此,建立精准、高效的鲍曼不动杆菌基因分型技术,是开展其医院内感染流行病学研究和临床防控的重要工具。本文就近年来鲍曼不动杆菌基因分型技术的研究进展进行综述,并分析比较多种基因分型技术的原理、优点、局限性及应用范围。

Acinetobacter baumannii,a non-fermentative Gram-negative bacterium,is known for its antibiotic resistance and clone transmission.A precise and effective genotyping method for Acinetobacter baumannii is essential to conduct epidemiological studies and control infections.The article reviews the recent progress on genotyping methods of Acinetobacter baumannii,and discusses the basic principles,advantages,limitations and application scope of these methods.