慢性阻塞性肺疾病合并肺血栓栓塞症的研究进展

Research progress on chronic obstructive pulmonary disease complicated with pulmonary thromboembolism

COPD是以持续呼吸道症状和持续气流受限为特征的慢性疾病。COPD常发生多种并发症,其中肺血栓栓塞症(PTE)是COPD患者的严重并发症之一。由于COPD合并PTE的临床表现不典型,且与COPD的症状部分重叠,易造成疾病的误诊、漏诊,严重影响患者预后及转归。该文通过对COPD合并PTE的流行病学特征、危险因素、发病机制、临床表现、诊断、临床防治及预后进行综述,以期进一步推动COPD合并PTE的临床诊疗。

Chronic obstructive pulmonary disease(COPD)is a chronic disease characterized with persistent respiratory symptoms and persistent airflow limitation.COPD can yield multiple complications and pulmonary thromboembolism(PTE)is one of the serious complications of COPD patients.It is likely to make a misdiagnosis and miss the diagnosis of COPD combined with PTE due to atypical clinical manifestations and overlap with partial COPD symptoms,which significantly affect the clinical outcomes and prognosis of COPD combined with PTE patients.In this paper,the epidemiological characteristics,risk factors,pathogenesis,clinical manifestations,diagnosis,clinical treatment and prevention,prognosis of COPD complicated PTE were reviewed,aiming to enhance the clinical diagnosis and treatment of COPD complicated with PTE.