脐尿管癌一例

Urachal carcinoma: one case report

脐尿管癌临床较少见,治疗预后欠佳。该病诊断主要依赖于病理及影像学检查,CT和MRI是常用检查手段,但仍需经病理检查才能确诊。该文报道1例脐尿管癌患者,因"脐部溢液1月余"就诊,行脐部肿物活组织病理学检查明确为黏液腺癌,接受经尿道膀胱镜检查术+脐尿管癌根治术2个月后出现全身多器官复发转移,先后经伊立替康+顺铂及奥沙利铂+希罗达等化学治疗后,病情仍进展,最终因肾衰竭死亡。该例患者病情进展快,对术后出现复发转移的晚期脐尿管癌患者治疗方案的选择仍需作进一步的研究探讨。

Urachal carcinoma is rare in clinical practice with poor clinical prognosis.The diagnosis of urachal carcinoma mainly depends upon pathological and imaging examinations.Computed tomography(CT)and magnetic resonance imaging(MRI)are common diagnostic tools,whereas the initial diagnosis remains to be confirmed by pathological staining.Here,we reported one case of urachal carcinoma due to umbilical discharge for over 1 month.Diagnosis of mucinous adenocarcinoma was confirmed through biopsy of the umbilical tumor.The patient underwent transurethral cystoscopy combined with radical resection of urachal carcinoma.At postoperative 2 months,systematic recurrence and metastasis of the urachal carcinoma was observed.After IP(irinotecan and cisplatin)and CapOX(capecitabine and oxaliplatin)chemotherapy,the urachal carcinoma still progressed.The patient died from renal failure.This case prompted rapid progression.The therapeutic strategies for advanced-stage urachal carcinoma in patients presenting with postoperative recurrence and metastasis remain to be explored and validated.