儿童过敏性鼻炎和鼻窦炎与哮喘严重程度的相关性分析

On Correlation between Allergic Rhinitis, Sinusitis and Asthma Severity in Children

目的探讨儿童哮喘患者中过敏性鼻炎和鼻窦炎的发病率及其与哮喘严重程度的关系。方法研究对象是125例(年龄<13岁)轻、中度哮喘儿童。过敏性鼻炎诊断是临床症状加鼻嗜酸性粒细胞增多;鼻窦炎诊断是临床症状加CT明确鼻窦病变。结果过敏性鼻炎发病率为13.6%,鼻窦炎发病率为2%。在多变量分析中,过敏性鼻炎、鼻窦炎和家族史与哮喘严重程度密切相关。结论过敏性鼻炎在儿童时期很常见,但鼻窦炎很少。过敏性鼻炎和鼻窦炎与儿童哮喘严重程度密切相关。

Objective To study the point prevalence of allergic rhinitis and sinusitis in childhood asthma and to examine the relationships among them.Methods In 150 children(age<13 y)with mild-to-moderate asthma,allergic rhinitis was diagnosed by clinical plus nasal eosinophilia criteria,and sinusitis was diagnosed clinically plus confirmation by computerized tomography scan.Results The point prevalence of allergic rhinitis was 13.6%,and of sinusitis was 2%.On multivariate analysis,allergic rhinitis,sinusitis,and family history were significantly associated with asthma severity.Conclusions Allergic rhinitis is common in childhood,but sinusitis is rare.Allergic rhinitis and sinusitis were significantly associated with asthma severity.