电针治疗卒中后便秘临床随机对照实验的Meta分析

RCTs Meta-analysis of Electro-acupuncture Treating Post-stroke Constipation

目的:评价电针治疗卒中后便秘的临床疗效,分析目前研究现状并为指导临床提供参考。方法:计算机检索中国知网、维普、万方数据库、Pubmed、Cochrane和Embase从建库至2017年8月发表的电针治疗卒中后便秘的随机对照研究,由两位评价员分别根据纳入排除标准筛选文献,提取资料并利用Cochrane评分对纳入研究进行质量评价。采用Review Manger5.3软件进行Meta分析。结果:共纳入研究11项,累计患者703人。Meta分析结果显示,电针组与对照组相比,总有效率[RR=1.20,95%CI(1.11,1.30),P<0.00001]、治愈率[RR=2.03,95%CI(1.50,2.73),P<0.00001]差异具有统计学意义。结论:本研究纳入的文献整体质量较差,仍需更多高水平论文来证明电针治疗卒中后便秘的确切疗效。

Objective:To evaluate the clinical efficacy of electro-acupuncture in the treatment of post-stoke constipation,to analyze the current research status,and to provide reference for its clinical application.Methods:RCTs of electro-acupuncture treating post-stoke constipation were retrieved from CNKI,Wanfang Data,VIP,Pubmed,Embase,and Cochrane from the establishment of the database to Aug.2017.The literatures were screened by two reviewers according to the inclusion-exclusion criteria,and the methodological quality was assessed by Cochrane score.Software Review manager 5.3 was used for Meta-analysis.Results:A total of 11 literatures were included in the study with 703 patients involved.The results of Meta-analysis showed that there were significant differences between the electro-acupuncture group and the control group in terms of the total efficacy[RR=1.20,95%CI(1.11,1.30),P<0.00001],effective rate[RR=2.03,95%CI(1.50,2.73),P<0.00001].Conclusion:Electro-acupuncture has a good therapeutic effect on constipation after stroke.However,the study needs more support with high-quality researches due to the limits of the number and quality of the included literatures.