复方六草消痤汤联合阿达帕林凝胶外用治疗丘疱疹型痤疮的疗效探讨

Curative Effect of Compound Liucaoxiaocuo Soup Combined with Adapalene Gel for the Treatment of Herpetic Acne

目的观察复方六草消痤汤联合阿达帕林凝胶外用治疗丘疱疹型痤疮的临床疗效,探讨其作用机理,为其推广提供理论依据。方法方便选取长春中医药大学附属医院在2013年6月—2014年5月治疗的90例符合标准的痤疮患者随机分为两组,观察其疗效及安全性:治疗组采用复方六草消痤汤加减联合阿达帕林凝胶外用;对照组采用阿达帕林凝胶外搽,观察2个月后各组疗效,比较治疗结果。半年后随访,复发情况。结果 2个疗程结束后,治疗组总有效率100.0%,对照组总有效率73.3%,两组疗效差异有统计学意义(P<0.05),两组均没有不良反应发生。半年后治疗组复发率6.6%,对照组复发率17.7%。结论复方六草消痤汤加减联合阿达帕林凝胶外用治疗丘疱疹型痤疮的临床疗效疗效高,安全可靠有显著优势,值得推广应用。

Objective This paper tries to observe the effect of compound Liucaoxiaocuo Decoction combined with Adapalene Gel treat Papulovesicles type Acne,to explore its action mechanism,to provide theoretical basis for its promotion.Methods 90 patients with acne vulgaris who were treated the affiliated hospital to Changchun University of Chinese Medicine from June 2013 to May 2014 were convenient selected and randomly divided into two groups to observe the efficacy and safety.Treatment group adopted compound Liucaoxiaocuo decoction,Adapalene Gel paint;The control group adopted Adapalene Gel paint;the curative effect was observed after 3 months.The curative effects were compared;6 months later,the recurrence was followed up.Results After 2 courses,the total effective rate of the treatment group was 100.0%,the other was 73.3%,and the difference was significant(P<0.05),and no adverse reactions occurred.After six months,the recurrence rate of the treatment group was 6.6%,and the control group was 17.7%.Conclusion The clinical curative effect of this therapy is high,safe and reliable.It has obvious advantages and is worthy of popularization and application.