神经电生理检查在运动神经元病中的应用及可行性研究

Research on Application and Feasibility of Nerve Electrophysiological Examination in the Motor Neuron Diseases

目的分析神经电生理检查应用在运动神经元病诊断中的可行性。方法方便选取50例运动神经元病患者(疾病组)和50名健康体检者(健康组)作为研究对象,时间为2014年7月—2016年6月。接受神经电生理检查,观察两组感觉神经、运动神经的波幅和传导速度、疾病组肌电图检测结果。结果疾病组运动神经中的腓总神经[波幅(5.12±2.36)m V、传导速度(47.56±2.62)m/s]、胫神经的波幅(15.34±4.56)m V、传导速度(45.21±4.15)m/s与健康组差别较大,感觉神经中尺神经的波幅(8.02±3.15)m V、正中神经的波幅(15.59±7.64)m V及传导速度(50.14±3.56)m/s和健康组差异有统计学意义(P<0.05);疾病组中进行性脊肌萎缩、肌萎缩侧索硬化的异常率与原发性侧索硬化和进行性球麻痹相比更高(P<0.05)。结论神经电生理检查应用在运动神经元病诊断中的可行性较高。

Objective To analyze the feasibility of Nerve electrophysiological examination in diagnosis of motor neuron diseases.Methods 50 cases of patients with motor neuron disease and 50 cases of healthy physical examination were convenient selected as the research objects from July 2014 to June 2016,both groups accepted the nerve electrophysiological examination,and the amplitude and conduction velocity of sensory nerve and motor nerve and electromyogram test result of the two groups were observed.Results The nervus peroneus communis[amplitude(5.12±2.36)mV,conduction velocity(47.56±2.62)m/s],amplitude and conduction velocity of nervi tibialis were respectively(15.34±4.56)mV and(45.21±4.15)m/s,and the differences were obvious compared with those in the health group,and the amplitude of nervi ulnaris of sensory nerve,amplitude of nervi medianus and conduction velocity were respectively(8.02±3.15)mV,(15.59±7.64)mV and(50.14±3.56)m/s,and the differences were obvious compared with those in the healthy group(P<0.05),and the abnormal rates of progressive spinal myodystrophia and amyotrophic lateral sclerosis were higher than those of primary lateral sclerosis and progressive bulbar palsy(P<0.05).Conclusion The feasibility of nerve electrophysiological examination in the motor neuron diseases is higher.