哮喘患儿肺炎衣原体及肺炎支原体感染的临床特征分析

Clinical Features of Chlamydia Pneumoniae and Mycoplasma Pneumoniae Infection in Children with Asthma

目的探讨哮喘患儿肺炎衣原体(CPn)及肺炎支原体(MPn)感染的临床特征。方法方便选取2015年6月—2017年6月该院80例哮喘患儿为研究对象,依据有无病原体感染分为实验组(CPn、MPn感染,常规治疗联合红霉素/阿奇霉素,40例)和对照组(非CPn、MPn感染,常规治疗,40例)。对比观察两组临床表现及并发症,评价疗效,观察实验组不同年龄及病程患儿的CPn、MPn感染率。结果实验组肺炎(82.5%)、间质性肺炎(30.0%)发生率高于对照组,差异有统计学意义(P<0.05),治疗总有效率(90.0%)与对照组(92.5%)比较差异无统计学意义(P>0.05)。结论哮喘患儿CPn、MPn感染多见于3岁以下或病程3个月以内,临床症状较非感染患者普遍严重,早期及时予以抗菌治疗效果确切,值得推广使用。

Objective This paper tries to investigate the clinical features of Chlamydia pneumoniae(CPn)and Mycoplasma pneumoniae(MPn)infection in children with asthma.Methods 80 cases of children with asthma from June 2015 to June 2017 were convenient selected in this hospital as the research objects,on the basis of a pathogen infection were divided into experimental group(CPn,MPn infection,conventional treatment combined with erythromycin/azithromycin,40 cases)and control group(non CPn,MPn infection,conventional treatment,40 cases).The clinical manifestations and complications of the two groups were compared and the curative effect was evaluated.The infection rates of CPn and MPn in children of different ages and course of the disease were observed.Results The incidence rate of pneumonia(82.5%)and interstitial pneumonia(30.0%)in experimental group was higher than that in control group(P<0.05),and the total effective rate(90.0%)was not significantly different from that of control group(92.5%)(P>0.05).Conclusion CPn and MPn infection in children with asthma are more seen in 3 years old or less than 3 months.The clinical symptoms are more serious than those of non infected patients.Early treatment with antibiotics is effective and worthy of promotion.