布拉氏酵母菌辅助治疗新生儿黄疸43例临床效果

Clinical effect of Saccharomyces boulardii in the adjuvant treatment of 43 cases of neonatal jaundice

目的观察布拉氏酵母菌辅助治疗在新生儿黄疸中的临床效果。方法将86例新生儿黄疸患者随机分为对照组和观察组,各43例。对照组给予常规治疗,观察组给予常规治疗+布拉氏酵母菌治疗。比较两组的治疗效果,治疗前、后血清总胆红素水平、血清胆红素日均下降值、黄疸消退时间及光疗时间。结果观察组的治疗总有效率显著高于对照组(P<0.05)。治疗后,两组的血清总胆红素水平均降低,且观察组低于对照组(P<0.05)。观察组的血清胆红素日均下降值高于对照组,黄疸消退时间早于对照组,光疗时间短于对照组(P<0.05)。结论新生儿黄疸给予布拉氏酵母菌辅助治疗,可提高治疗效果,促进血清胆红素水平下降,值得临床推广。

Objective To observe the clinical efficacy of Saccharomyces boulardii in the adjuvant treatment of neonatal jaundice.Methods Eighty-six cases of neonatal jaundice were randomly divided into control group and observation group,with 43 cases in each group.The control group was given routine treatment,and the observation group was treated with Saccharomyces boulardii on the basis of routine treatment.The treatment effects,serum total bilirubin levels before and after the treatment,daily decline of serum bilirubin,time of jaundice disappearance and time of phototherapy were compared between the two groups.Results The total effective rate of treatment in the observation group was significantly higher than that in the control group(P<0.05).After treatment,the serum total bilirubin levels in the two groups decreased,and that of the observation group was lower than the control group(P<0.05).The daily decline of serum bilirubin in the observation group was higher than that in the control group(P<0.05).The time of jaundice disappearance was earlier than that in the control group,and the time of phototherapy was shorter than that in the control group(P<0.05).Conclusion Saccharomyces boulardii in the adjuvant treatment of neonatal jaundice can improve the therapeutic effect and promote the decrease of serum bilirubin level,which is worthy of clinical promotion.