舒芬太尼联合格拉司琼应用于腹部手术患者的临床效果

Clinical effect of sufentanil and granisetron in patients undergoing abdominal surgery

目的探讨舒芬太尼+格拉司琼在腹部手术后患者中的应用价值,分析其对患者术后生命体征、疼痛以及不良反应的影响。方法将我院收治的接受腹部手术的患者94例随机分为对照组和观察组,各47例。对照组术后给药方案为舒芬太尼+昂丹司琼,观察组为舒芬太尼+格拉司琼。观察两组术后不同时段的生命体征、疼痛变化以及不良反应发生率。结果观察组T2、T3的MAP均高于对照组,差异具有统计学意义(P<0.05);两组T4的VAS评分显著低于术前T1,差异有统计学意义(P<0.05);观察组不良反应发生率低于对照组的,差异有统计学意义(P<0.05)。结论舒芬太尼联合格拉司琼能减少腹部手术患者术后的平均动脉压波动,不良反应少,安全性高,值得临床推广。

Objective To explore the application value of sufentanyl+grascham in patients undergoing abdominal surgery,and analyze its effects on postoperative vital signs,pain and adverse reactions.Methods A total of 94 patients with abdominal surgery admitted in our hospital were randomly divided into control group and observation group,with 47 cases in each group.The control group was treated with sufentanil+ondansetron after operation,the observation group was treated with sufentanil+granisetron after operation.The postoperative vital signs,changes in pain and incidence of adverse reactions of the two groups were observed.Results The MAP levels of T2 and T3 in the observation group were higher than those in the control group(P<0.05).The VAS scores of T4 of the two groups were significantly lower than those of T1,and the differences were statistically significant(P<0.05).The incidence rate of adverse reactions of the observation group was significantly higher than that of the control group(P<0.05).Conclusion Sufentanil combined with granisetron can reduce the average arterial pressure fluctuation in patients undergoing abdominal surgery,with less adverse reactions and high safety,which is worthy of clinical promotion.