摘要
目的提高对肝癌膈下动脉经动脉导管化疗栓塞术(TACE)并发脊髓损伤的认识。方法回顾分析1例肝癌膈下动脉TACE并发脊髓损伤患者的临床资料,结合相关文献报道,探讨其可能的发病机制、危险因素、治疗和康复预后情况。结果膈下动脉同脊髓供血动脉之间的交通支开放是TACE导致脊髓损伤的解剖学基础,而造影剂、化疗药、栓塞剂和治疗介入次数均可成为脊髓损伤的致病因素。这种脊髓损伤多是一过性的,绝大部分患者经过早期康复治疗均可在发病数周至数月内得到良好的功能恢复。结论肝癌行经膈下动脉TACE并发脊髓损伤非常少见,在早期发现和得到及时的康复治疗后,功能预后较好。
Objective To further explore the complication of spinal cord injury occured after transcatheter arterial chemoembolization(TACE)for hepatocellular carcinoma via inferior phrenic artery.Methods The clinical and imaging data of one patient with spinal cord injury caused by TACE for hepatocellular carcinoma via inferior phrenic artery was retrospectively analyzed.The pathologic mechanism,risk factors and outcome of rehabilitative treatment were discussed after literature review.Results The abnormal opening of communicating branches between inferior phrenic artery and spinal cord blood supplying was the underlying mechanism inducing spinal cord injury after TACE.The risk factors included contrast agent,chemotherapy drug,embolic agent,and multiple interventional therapy,etc.Most patients returned almost to normal state within several months after early rehabilitation.
作者
刘宏炜
李军
杜良杰
LIU Hong-wei;LI Jun;DU Liang-jie(Department of Spinal and Neural Functional Reconstruction,Beijing Bo'ai Hospital,China Rehabilitation Research Center,Beijing 100068,China;Capital Medical University School of Rehabilitation Medicine,Beijing 100068,China)
出处
《中国康复理论与实践》
CSCD
北大核心
2018年第4期472-476,共5页
Chinese Journal of Rehabilitation Theory and Practice
关键词
肝癌
化疗栓塞术
脊髓损伤
危险因素
康复
预后
hepatocellular carcinoma
transcatheter arterial chemoembolization
spinal cord injury
risk factors
rehabilitation
outcome
