阿奇霉素不同疗程在治疗小儿肺炎支原体肺炎中的临床效果观察

Clinical Effect of Azithromycin in Different Courses of Treatment for Mycoplasma Pneumoniae Pneumonia in Children

目的分析小儿肺炎支原体肺炎使用阿奇霉素不同疗程治疗的临床效果。方法选取了90例小儿肺炎支原体肺炎患儿进行分析,为患儿进行了分组,使用不同的剂量,对照组和观察组均有45例患儿。对照组使用阿奇霉素治疗,疗程≤5天,观察组使用7天疗程,对两组的治疗效果、症状消失时间、不良反应等情况进行比较分析。结果观察组临床治疗有效率是91.11%,对照组的临床治疗有效率是75.56%,两组结果差异存在统计学意义(P<0.05);观察组患者和对照组患者的退热时间对比差异不存在统计学意义(P>0.05);对照组不良反应率是2.22%,观察组没有不良反应病例,差异无统计学意义(P>0.05)。结论阿奇霉素滴注7天的肺炎支原体肺炎患儿治疗时间比较短,X线阴影消失时间、住院时间比较短,没有不良反应。

Objective To study and analyze the clinical effect of difference courses of azithromycin treatment for mycoplasma pneumoniae pneumonia in children.Methods 90 cases of children with mycoplasma pneumoniae pneumonia were selected,45 cases in the control group and the observation group.The control group was treated with azithromycin for less than 5 days,and the observation group was treated for 7 days.The therapeutic effect,symptom disappearance time and adverse reactions of the two groups were compared.Results The clinical observation of the effective rate in observation group was 91.11%,the effective rate of control group was 75.56%,there was significant difference of the results of the two groups(P<0.05);the cooling time between two groups had no statistical differences(P>0.05);adverse reaction rate in the control group was 2.22%,the observation group had no cases of adverse reactions,the results were not statistically difference(P>0.05).Conclusion Azithromycin instillation for 7 days in children with mycoplasma pneumoniae pneumonia has shorter treatment time,shorter time of X-ray shadow and shorter hospitalization time.There is no adverse reaction.