血清降钙素原和C反应蛋白检测对于肺部感染患者的临床价值研究

Clinical Value of Serum Procalcitonin and C Reactive Protein in Patients With Pulmonary Infection

目的探讨血清降钙素原(PCT)和C反应蛋白(CRP)检测对于肺部感染患者的临床诊断价值。方法 200例肺部感染患者,根据病情的严重程度分为重度感染组86例,轻中度感染组114例,另选取我院同期的健康体检者100例作为对照组。三组受试者均于清晨抽取空腹静脉血5 ml,采用免疫比浊法测定CRP,电化学发光法测定PCT,比较三组受试者PCT和CRP水平。结果三组受试者PCT和CRP水平差异具有统计学意义(P<0.05),重度感染组高于轻中度感染组以及对照组(P<0.05),轻中度感染组高于对照组(P<0.05)。结论 PCT和CRP检测有助于肺部感染的鉴别与严重程度的评估。

Objective To investigate the clinical value of serum procalcitonin(PCT)and C reactive protein(CRP)in patients with pulmonary infection.Methods 200 cases of pulmonary infection were divided into severe infection group(86 cases)and mild-moderate infection group(114 cases)according to the severity of the infection.100 cases of healthy physical examination were selected as control group in the same period.In the three groups,5 ml was extracted from fasting venous blood in the early morning.CRP was measured by immuno turbidimetry,and PCT was measured by electrochemiluminescence.PCT and CRP levels in three groups were compared.Results There were significant differences among three groups in PCT and CRP levels(P<0.05).PCT and CRP levels in severe infection group were significantly higher than those in mildmoderate infection group and control group(P<0.05).PCT and CRP levels in mild-moderate infection group were significantly higher than those in control group(P<0.05).Conclusion PCT and CRP tests can help identify and assess the severity of pulmonary infection.