原发性肝癌TACE治疗后并发上消化道出血的原因及处理

Causes and Treatment of Acute Hemorrhage of Upper Digestive Tract after Chemo-Embolization for Primary Hepatitic Carcinoma

原发性肝癌是世界性常见的恶性肿瘤之一,肝癌的早发现、早治疗已成为临床研究的重点。经导管肝动脉化疗栓塞术(TACE)是目前唯一证实对预后有益的治疗手段,该方法具有在进行药物化疗的同时还可以有效阻断肿瘤的动脉血供的特点。由于临床上原发性肝癌发病隐匿,病情进展迅速,转移发生较早,许多病例不适宜手术切除,因此,TACE成为中晚期肝癌患者的首选治疗方法。TACE的治疗方法存在术后不良反应并伴有并发症的发生。了解TACE治疗后并发上消化道出血发生的机制和有效的处理方法对提高TACE治疗肝癌的效果有重要价值。

Primary liver cancer is a common malignancy worldwide.Early detection and early treatment of liver cancer has become the focus of clinical research.Transcatheter arterial chemoembolization(TACE)is the only treatment that has proved beneficial to the prognosis.This method can effectively block the arterial blood supply of tumor during chemotherapy.Due to the occult onset,rapid progress and early metastasis of primary hepatocellular carcinoma in clinical,many cases are not suitable for surgical resection.Therefore,TACE is the preferred treatment for patients with advanced liver cancer.The treatment of TACE is accompanied by postoperative adverse reactions and complications.Understanding the mechanism and effective treatment of upper gastrointestinal hemorrhage after TACE treatment has great value to improve the effect of TACE on liver cancer.