“全时段采血”在餐前和餐后临床化学检测项目中的结果比较

Comparison of preprandial and postprandial test results of clinical chemistry tests

目的在"全时段采血"实施的背景下探讨餐后采血对临床化学检测项目的影响。方法选取健康志愿者30名,分别于餐前和餐后2、4h采集静脉血检测肝脏功能、心肌功能、肾脏功能、血脂、电解质等相关的47个临床生化指标,分析其差异。结果总胆红素(TBIL)和直接胆红素(DBIL)的餐后2h和4h结果显著低于餐前(P<0.05),且餐后4h结果低于餐后2h(P<0.05);餐后2h和4h的肌酸激酶(CK)和三酰甘油(TG)结果显著高于餐前(P<0.05),且餐后4h结果高于餐后2h(P<0.05);餐后2h的葡萄糖(GLU)结果显著高于餐前(P<0.05),4h后降至餐前水平。其他大部分临床化学指标在餐前和餐后检测结果差异无统计学意义(P>0.05)。结论餐后4h内采血检测临床生化指标,其大部分检测数据能满足临床诊治的需求,"全时段采血"值得在更多类型患者和更大范围时间内进行实践。

Objective Under the background of"full-time blood collection",we explored the effect of diet on the clinical biochemical indexes.Methods A total of 47 clinical biochemical indexes including liver function,myocardium function,kidney function,lipids and electrolytes were determined in the serum form 30 health individuals,at the time points which were fasting and postprandial(2 h and 4 h).Results The postprandial 2 h and 4 h results of TBIL and DBIL were significantly lower than fasting respectively(P<0.05),and the results were lower than that of postprandial 2 h(P<0.05).The postprandial 2 h and 4 h CK and TG results were significantly higher than that of fasting results respectively(P<0.05),and the results of postprandial 4 h was higher than that of postprandial 2 h(P<0.05).The postprandial 2 h GLU results was significantly higher than that of fasting(P<0.05);the GLU levels down to fasting levels 4 h after the meal.There was no significant difference of the results between fasting and postprandial in most of the other clinical chemical indicators(P>0.05).Conclusion Most of the test data of postprandial 4 h can meet the needs of clinical diagnosis and treatment;the"full-time blood collection"is worth practicing in more types of patients and in a wider range of time.