针灸联合加味补阳还五汤治疗PSD的疗效及对HAMD SDS BECK量表结果的影响

Therapeutic Effect of Acupuncture Combined with Modified Bu Yang Huan Wu Soup on PSD and its Influence on the Results of HAMD SDS and BECK Scales

目的:探讨针灸联合加味补阳还五汤治疗卒中后抑郁(PSD)的疗效及对汉密尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)、贝克抑郁自评量表(BECK)结果的影响。方法:本研究对象选取84例PSD患者,按照随机数字表法分成2组,每组42例。对照组患者给予口服加味补阳还五汤治疗,观察组患者给予针灸联合加味补阳还五汤治疗。连续治疗4周,对比两组临床疗效、血清炎症因子水平、HAMD、SDS、BECK量表结果的差异。结果:治疗后对照组显效15例、有效18例、无效9例,总有效率为78.57%。观察组显效21例、有效19例、无效2例,总有效率为95.24%,组间有显著的统计学差异(P<0.05)。治疗前两组患者HAMD、SDS、BECK量表评分无统计学差异(P>0.05);治疗后观察组患者HAMD、SDS、BECK量表评分均低于对照组,组间有显著的统计学差异(P<0.05)。结论:采用针灸联合加味补阳还五汤治疗卒中后抑郁的疗效显著,可降低抑郁评分,使患者的抑郁症状得到更好的改善。

Objective:To explore the effect of acupuncture combined with Jiawei Buyang Five Decoction on post-stroke depression(PSD)and its effect on the results of Hamilton Depression Scale(HAMD),self rating Depression Scale(SDS)and Beck self rating Depression Scale(BECK).Methods:84 patients with PSD were selected and divided into 2 groups according to the random number table method,with 42 cases in each group.The patients in the control group were treated with oral administration of Buyang Huanwu Decoction and five decoction.The observation group was treated with acupuncture combined with modified Buyang Huanwu Decoction and five decoction.The clinical efficacy,serum inflammatory factors,HAMD,SDS and BECK scales were compared between the two groups after 4 weeks of continuous treatment.Results:After treatment,the control group was markedly effective in 15 cases,effective in 18 cases,ineffective in 9 cases,the total effective rate was 78.57%.The observation group was markedly effective in 21 cases,effective in 19 cases and ineffective in 2 cases,the total effective rate was 95.24%,and there was a statistically significant difference between the two groups(P<0.05).Two groups of patients before treatment of HAMD,SDS and BECK scores showed no significant difference(P>0.05);after treatment,the observation group were HAMD,SDS and BECK scores were lower than the control group,there was a significant difference between the groups(P<0.05).Conclusion:Acupuncture combined with modified Buyang Huanwu five decoction is effective in the treatment of post-stroke depression.It can reduce the depression score,and improve the depressive symptoms of patients.