黄芪补胃汤加味合贴脐散治疗脾胃虚弱型腹泻型肠易激综合征的临床疗效观察

Clinical observation on treating diarrhoea predominant irritable bowel syndrome of the Piwei Xuruo type with the Huangqi Buwei decoction plus Tieqi San

目的:观察黄芪补胃汤加味合贴脐散治疗脾胃虚弱型的腹泻型肠易激综合征(IBS)的临床疗效,为临床治疗提供科学依据。方法:选取我院2015年6月-2016年6月收诊的腹泻型肠易激综合征的脾胃虚弱型患者150例,随机分为3组,每组各50例。其中联合组给予黄芪补胃汤加味合贴脐散治疗,中药组给予黄芪补胃汤加味,对照组则给予蒙脱石散治疗。所有患者的疗程均为7d,治疗前及治疗4个疗程后分别进行中医证候积分,对积分结果进行统计并分析。结果:联合组、中药组及对照组的总有效率分别是94%、80%、64%,其中,联合组与中药组的总有效率高于对照组(P<0.05),联合组的总有效率高于中药组(P<0.05)。三组治疗后中医证候积分均较前降低(P<0.05),其中,联合组治疗后的中医证候积分显著低于中药组及对照组(P<0.05)。结论:黄芪补胃汤加味合贴脐散治疗腹泻型肠易激综合征的脾胃虚弱型疗效明显,值得临床推广使用。

Objective:To observe the clinical effect of the Huangqi Buwei decoction(黄芪补胃汤)plus Tieqi San(贴脐散)on diarrhea predominant irritable bowel syndrome,and provide scientific basis for clinical treatment.Methods:150 patients were randomly divided into three groups,50 cases in each.The combined group was given the Huangqi Buwei decoction plus Tieqi San.The TCM group was given the Huangqi Buwei decoction.The control group was given montmorillonite powder.All the patients were treated for 7 days.TCM syndrome scores were counted and analyzed before treatment and after 4 courses.Results:The total effective rate was 94%,80%,and 64%in the combined group,the TCM group and the control group respectively.The total effective rate in the combined group and the TCM group was higher than that in the control group,and that in the combined group was higher than the TCM group.The scores of TCM syndromes in three groups were lower than before(P<0.05).The scores of TCM syndromes in the combined group were significantly lower than those in the TCM group and the control group(P<0.05).Conclusion:The Huangqi Buwei decoction plus Tieqi San on diarrhoea predominant irritable bowel syndrome of the Piwei Xuruo type(脾胃虚弱型)shows a significant effect,and is worthy of application in clinic.