清热除痹汤治疗急性痛风疗效及安全性评价

Safety and clinical efficacy of the Qingre Chubi decoction on acute gout

目的:针对急性痛风患者应用清热除痹汤进行治疗,并探究分析其疗效与安全性。方法:选择78例患者作为本次研究对象,均为2016年6月-2017年6月在本院治疗的急性痛风患者,以投掷法将其随机分成两组,其中应用西药治疗的39例患者作为对照组,另外应用清热除痹汤治疗的39例患者作为观察组,对比分析两组患者药物治疗效果及不良反应情况。结果:治疗后对照组中无效13例(33.33%),有效26例(66.67%),观察组中无效2例(5.13%),有效37例(94.87%),组间差异具有统计学意义(P<0.05);治疗后对照组不良反应共发生11例(28.21%),显著高于观察组的1例(2.56%),组间差别具有统计学意义(P<0.05)。结论:急性痛风患者应用清热除痹汤治疗效果较为显著,且安全可靠,不良反应少,建议广泛应用。

Objective:To evaluate safety and the clinical effects of the Qingre Chubi decoction(清热除痹汤)on acute gout.Methods:78 patients were randomly divided into two groups,39 cases in each group.The control group took western medicine.The observation group took the Qingre Chubi decoction more.Results:After treatment,in the control group,13 cases(33.33%)were invalid,and 26 cases(66.67%)were valid;in the observation group,2 cases(5.13%)were invalid,and 37 cases(94.87%)were valid(P<0.05).After treatment,the adverse event rate in control group(28.21%)was significantly higher than 2.56%in the observation group(P<0.05).Conclusion:The Qingre Chubi decoction was effective on acute gout,can greatly improve the clinical safety and reduce the adverse events.