硫酸氢氯吡格雷与阿司匹林治疗冠心病的效果及不良反应对比研究

Comparison on the effects and adverse reactions of clopidogrel and aspirin in the treatment of coronary heart disease

目的:探讨硫酸氢氯吡格雷与阿司匹林治疗冠心病的效果及不良反应。方法:收治冠心病患者76例,分为观察组和对照组,各38例。观察组给予阿司匹林治疗,对照组给予硫酸氢氯吡格雷治疗。结果:治疗后,观察组血小板聚集率及凝血功能改善效果大于对照组(P<0.05),观察组不良反应发生率低于对照组(P<0.05)。结论:硫酸氢氯吡格雷治疗冠心病具有较高的临床价值,能够在保证安全性的前提下发挥显著的疗效。

Objective:To investigate the effects and adverse reactions of clopidogrel and aspirin in the treatment of coronary heart disease(CHD).Methods:76 patients with coronary heart disease were selected.They were divided into the observation group and the control group,with 38 cases in each group.The observation group were treated with aspirin,while the control group were treated with clopidogrel hydrogen sulfate.Results:After the treatment,the improvement rate of platelet aggregation and improving of coagulation function in the observation group were greater than that in the control group(P<0.05),and the incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).Conclusion:Clopidogrel sulfate has high clinical value in the treatment of coronary heart disease,and it can play a significant effect on the premise of ensuring safety.