补肺壮精方对精子形态、精浆生化及精液参数的影响

Effects of Bufei Zhuangjing Fang on Sperm Morphology,Seminal Plasma Biochemistry and Semen Parameters

目的:研究补肺壮精方对精子形态、精浆生化及精液参数的影响。方法:将120例男性不育患者随机分为2组,每组60例。方法:治疗组服用补肺壮精方(黄芪、桑白皮、天冬、麦冬、知母、桑叶、桑螵蛸、枳壳、菟丝子、制何首乌、沙苑子、茯苓)治疗,对照组服用五子衍宗方(菟丝子、覆盆子、枸杞子、车前子、五味子)治疗。2个月为1疗程。主要观察治疗前后精子活力、α-中性糖苷酶、精浆果糖及精子形态的变化。结果:治疗组总有效率为86.67%、显效15例、无效8例,对照组总有效率为68.33%、显效9例、无效19例,2组总有效率比较,差异有显著性(P<0.05);治疗后2组患者精浆果糖、糖苷酶及精子形态正常率较治疗前均有显著性升高(P<0.05),但各指标改善情况治疗组均优于对照组,差异有显著性(P<0.05);治疗后2组患者精液参数均高于治疗前(P<0.05),但各指标改善情况治疗组均优于对照组,差异有显著性(P<0.05)。结论:补肺壮精方可以明显提高精子活力并改善精子形态。

Objective:To study the effect of Bufei Zhuangjing Fang on sperm morphology,seminal plasma biochemistry and semen parameters.Methods:120 male infertility patients were randomly divided into 2 groups,60 cases in each group.Methods:the treatment group took Bufei Zhuangjing Fang(huangqi,sangbaipi,tiantong,maidong,zhimu,sangye,sangpiaoxiao,zhiqiao,tusizi,zhi heshouwu,shayuanzi and fuling),and the control group was treated with Wuzi Yansong Fang(Five-Seed Progeny Recipe)(tusuzi,fupenzi,gouqizi,cheqianzi and wuweizi).2 months is a course.Sperm motility,alpha neutral glucosidase,seminal fructose and sperm morphology were observed before and after treatment.Results:the total effective rate of the treatment group was 86.67%with 15 cases effective and 8 cases ineffective.The total effective rate of the control group was 68.33%with 9 cases effective and 19 cases ineffective.There was significant difference(P<0.05).The normal rate of the seminal fructose,glucosidase and sperm morphology in the 2 groups were significantly higher than before the treatment(P<0.05).But the treatment group was better than the control group with significant difference(P<0.05).The semen parameters of the 2 groups were higher than those before the treatment(P<0.05),but the improvement of the indexes in the treatment group was superior to the control group,and the difference was significant(P<0.05).Conclusion:Bufei Zhuangjing Fang can significantly promote sperm motility and improve sperm morphology.