VSD联合表皮生长因子治疗软组织损伤的效果观察

Effect of VSD combined with EGF in treatment of soft tissue injury

目的探讨负压封闭引流(VSD)联合表皮生长因子治疗软组织损伤的临床效果。方法选择医院收治的117例骨科软组织损伤患者,根据治疗方式不同分为3组,各39例。A组给予VSD技术治疗,B组采用表皮生长因子治疗,C组采用VSD联用表皮生长因子治疗。观察比较3组临床治疗效果、创面愈合时间及创面愈合情况。结果 C组临床治疗总有效率、创面愈合时间、创面甲级愈合率均明显优于其他两组(P<0.05);而A组与B组之间比较无显著差异(P>0.05)。结论骨科软组织损伤应用VSD联合表皮生长因子进行治疗,能够有效促进创面修复组织生长,显著缩短创面愈合时间,提高创面愈合质量,且美容效果好。

Objective To explore the clinical effects of vacuum sealing drainage(VSD)combined with epidermal growth factor(EGF)in the treatment of soft tissue injury.Methods A total of 117 patients"with soft tissue injury admitted into Department of Orthopedics of our hospital were selected and divided into three groups according to the treatment method(n=39,respectively).VSD technical treatment was perfor^ned on Group A,EGF treatment was perfor^ned on Group B,and VSD+EGF treatment was perfor^ned on Group C.Observations were made on the clinical effects,wound healing periods and wound healing conditions of the groups.Results The total effective rate of treatment,wound healing period and class-A wound healing rate in Group C were significantly superior to other two groups(P<0.05),and there were no significant differences between Group A and Group B(P>0.05).Collusion VSD combined with EGF in the treatment of soft tissue injury can effectively accelerate the growth of wound healing tissues,significantly shorten the wound healing period,improve the wound healing quality,and achieve ideal cosmetic result.