老年人群慢性萎缩性胃炎与肌少症的相关性分析

Correlation between chronic atrophic gastritis and sarcopenia in senile people

目的研究老年慢性萎缩性胃炎与肌少症的相关性。方法选择就诊于医院消化内科门诊及住院的年龄大于70岁慢性胃炎患者163例,按胃镜活检病理报告分为慢性非萎缩性胃炎组和慢性萎缩性胃炎组两组,比较两组体重指数(BMI)、微型营养评估简易法(MNA-SF)评分、前白蛋白、白蛋白及肌少症等指标的差异,并分析慢性萎缩性胃炎与肌少症的相关性。结果慢性萎缩性胃炎组的HP阳性率显著高于慢性非萎缩性胃炎组(P<0.05),BMI、MNA评分、白蛋白及前白蛋白含量显著低于慢性非萎缩性胃炎组(P<0.05)。慢性萎缩性胃炎组握力、步速及RASM均显著低于慢性非萎缩性胃炎组(P<0.05),慢性非萎缩性胃炎肌少症患病率(12.3%)显著低于慢性萎缩性胃炎组(20.39%)(P<0.05)。结论老年慢性萎缩性胃炎患者HP感染率高,营养状况差,肌少症患病率高,此类患者应加强营养支持,并注意监测HP感染情况,必要时进行抗HP治疗。

Objective To explore the correlation between chronic atrophic gastritis and sarcopenia in senile people.MeAods A total of 163 patients aged over 70 with chronic gastritis treated as outpatients or hospitalized at the Department of Gastroenterology in our hospital were chosen as the subjects for research,and were divided into a chronic non-atrophic gastritis group and a chronic atrophic gastritis group to compare the differences in body mass index(BMI),MNA-SF scores,prealbumin,albumin and sarcopenia and analyze the correlation between chronic atrophic gastritis and sarcopenia.Results The HP positive rate of the chronic atrophic gastritis group was significantly higher than that of the chronic non-atrophic gastritis group(P<0.05)while BMI,MNA scores,albumin and prealbumin contents were significantly lower than those of the chronic non-atrophic gastritis group(P<0.05).The chronic atrophic gastritis group was significantly inferior to the chronic non-atrophic gastritis group in grip,leg speed and RASM(P<0.05).The chronic non-atrophic gastritis group showed a significantly lower sarcopenia incidence(12.3%)than the chronic atrophic gastritis group(20.39%)(P<0.05).Conclusion Senile patients with chronic atrophic gastritis show a high HP infection rate,poor nutritious condition and high incidence of sarcopenia.These patients shall obtain more nutritious support and be subject to HP infection monitoring,and anti-HP treatment when necessary.