临床药师联合多部门干预对曲克芦丁脑蛋白水解物使用效果分析

Effects of intervention on use of troxerutin cerebroprotein hydrolysate injection by clinical pharmacists in combination with other departments

目的:探讨临床药师联合多部门在干预曲克芦丁脑蛋白水解物注射液等重点监控药品合理使用中的作用与效果。方法:采用回顾性的研究方法,对2017年7–10月我院所有应用曲克芦丁脑蛋白水解物注射液的病历进行分析,对比联合干预前后该药在临床用量及合理性等情况。结果:连续干预后曲克芦丁脑蛋白水解物注射液用量及使用人数较干预前有明显的减少,占重点监测用药金额比例从9.87%下降至1.78%,合理用药率从干预前41.8%提高到干预后90.5%,差异有显著统计学意义(P<0.01)。其中,干预后使用时间不合理率从干预前32.68%下降至6.52%,联合用药不合理率从干预前28.10%下降至4.76%,两者相比差异均具有统计学意义(P<0.01),处罚情况较干预前有明显的好转。结论:临床药师联合多部门干预后,临床合理使用曲克芦丁脑蛋白水解物有明显的提升,为重点监控用药管理提供了更好的基础,为临床药师下一步开展医保控费及单品种控费等用药工作提供了有力的保障。

Objective:To investigate the effect of intervention on use of troxerutin cerebroprotein hydrolysate injection by clinical pharmacists and other surgical departments of our hospital.Methods:Data of the patients treated with troxerutin cerebroprotein hydrolysate injection in our hospital from July 2017 to October 2017 was collected and retrospectively analyzed focusing on the amount of troxerutin cerebroprotein hydrolysate injection and rationality before and after intervention.Results:The amount of troxerutin cerebroprotein hydrolysate injection and the number of patients who used troxerutin cerebroprotein hydrolysate injection were obviously reduced after intervention,among all the key monitoring drugs,the cost ratio of troxerutin cerebroprotein hydrolysate dropped from 9.87%to 1.78%.The ratio of rational drug use of troxerutin cerebroprotein hydrolysate increased from 41.8%before intervention to 90.5%after intervention and there were significant differences between them(P<0.01).The ratio of unreasonalbe time of drug use dropped from 32.68%before intervention to 6.52%after intervention(P<0.01)and ratio of unreasonable drug combination dropped from 28.10%before intervention to 4.76%after intervention(P<0.01).Conclusion:Clinical pharmacist's intervention together with other departments could obviously improve the rational use of troxerutin cerebroprotein hydrolysate injection,which could provide good foundation for the key drug monitoring.