摘要
目的:观察自拟通络熄风方治疗老年糖尿病合并急性脑卒中的临床疗效。方法:选取120例老年糖尿病合并急性脑卒中患者,按治疗方式不同分为观察组和对照组,对照组(n=60)实施常规西医治疗,观察组(n=60)在常规西医基础上给予通络熄风方治疗,比较两组神经功能缺损评分、Hb A1c水平、ADL评分、FBG和血管内皮功能指标,比较两组患者临床疗效。结果:观察组治疗总有效率为90.00%,显著高于对照组的73.33%(P<0.05);治疗后,观察组神经功能缺损评分、Hb A1c水平低于对照组,ADL评分、FBG高于对照组(P<0.05);对照组治疗后各血管内皮功能指标与治疗前无统计学差异(P>0.05),观察组治疗之后,ET-1、TXB2较治疗前明显下降,NO较治疗前升高(P<0.05)。结论:在西医常规治疗基础上采用自拟通络熄风方治疗老年糖尿病合并急性脑卒中的临床疗效优于单纯西医常规治疗。
Objective:To observe clinical effects of self-made Tongluoxifeng prescription in elderly patients with diabetes mellitus with acute cerebral apoplexy.Methods:120 cases of elderly diabetic patients with acute cerebral apoplexy were selected and divided into observation group(n=60)and control group(n=60)according to the different treatment methods.The control group was given the conventional western medicine treatment,while the observation group used Tongluoxifeng prescription based on that of the control group.The neurologic impairment score,HbA1c level,ADL score,FBG and vascular endothelial function indexes were evaluated.Further,the clinical effects of the two groups were compared.Results:The total effective rate of the observation group(90.00%)was significantly higher than that of the control group(73.33%),and the difference was statistically significant(P<0.05).After the treatment,the neurologic impairment score and HbA1c level of the observation group were lower than those of the control group,however,the ADL score and FBG were higher than those of the control group.There were no statistical differences in the vascular endothelial function indexes in the control group before and after the treatment(P>0.05).After the treatment,the ET-1 and TXB2 levels were significantly reduced and NO level increased(P<0.05).Conclusions:On the basis of the conventional western medicine treatment,Tongluoxifeng prescription in the elderly patients with diabetes mellitus with acute cerebral apoplexy is superior to single conventional western medicine treatment.
作者
毛仲岐
武继涛
MAO Zhongqi;WU Jitao(Fanxian County TCM Hospital,Puyang Henan 457500,China;The First Affiliated Hospital of Henan University of TCM)
出处
《中国民康医学》
2018年第5期78-79,82,共3页
Medical Journal of Chinese People’s Health
关键词
中西医结合
通络熄风方
老年糖尿病
急性脑卒中
Integrated traditional Chinese and western medicine
Tongluoxifeng prescription
Elderly diabetes
Acute cerebral apoplexy