成软骨细胞瘤在扁骨的CT/MRI表现

The CT/MRI Manifestations of Chondroblastoma in the Flat Bone

目的探讨扁骨成软骨细胞瘤CT和MRI动态增强中的影像表现,提高对罕见肿瘤的影像学认识。方法系统性分析经病理证实的8例扁骨成软骨细胞瘤的多种影像学资料,分析其病灶位置、形态、密度及CT/MRI增强表现等征象。结果 8例入组病人中成软骨细胞瘤病灶位于颅骨的5例,位于髌骨3例。病灶呈不规则形,以膨胀性骨破坏为主,周围可见完整或不完整的硬化缘,其内有或无分隔,病灶内偶尔可见点状及片状钙化。病灶MRI的增强影像主要表现为不均匀混杂的T1、T2信号,增强呈明显不均强化。结论成软骨细胞瘤发生于扁骨时,病灶膨胀,内见斑点状钙化,基质明显强化为主要特征。由于病例较少,为避免误诊,应结合临床、影像学和病理学特征进行综合诊断。

Objective To explore the diagnostic imageological characteristics of chondroblastoma in flat bone.Methods Various imageological data from eight cases of pathologically confirmed flat bone chondroblastoma were systematically studied,where the features encompassing lesions position,morphology,density and performances of CT/MRI dynamic enhancement were analyzed.Results Five out of eight cases of chondroblastoma lesions were located on skull,the other three were located on patella.These lesions mainly appeared as rounded or irregular shapes with expansive osteolytic bone destruction under computerized tomography(CT)scan,represented noticeable holonomic or nonholonomic sclerosing margin with or without inner demarcation,and showed patchy or punctate calcification sporadically.The lesions also exhibited inhomogenous mixed T1 and T2 signals and remarkable uneven enhancements under Magnetic resonance imaging(MRI).Conclusion Chondroblastoma in flat bone was mainly featured as expansile lytic lesion with punctate calcification and stroma enhancement under both CT and MRI scan.Nevertheless,clinic,imageology and pathology should be comprehensively integrated for precise diagnosis considering the low incidence of Chondroblastoma in flat bone.