血清降钙素原在新生儿感染早期的诊断价值分析

The Diagnostic Value of Serum Calcitonin in Early Neonatal Infection

目的分析血清降钙素原在新生儿感染早期的诊断价值。方法选择2015年6月—2017年6月我院收治的98例疑似感染新生儿为研究对象,设立为感染组;另取同期98名健康新生儿作为健康组,测定血液内血清PCT以及CPR,分析结果。结果与健康组相比,感染组的PCT以及CRP值明显较高,差异均具有统计学意义(P<0.05)。CRP的特异性,阳性预测值比PCT高,灵敏性、阴性预测值以及约登指数比PCT低,组间数据对比,差异均具有统计学意义(P<0.05)结论在早期检测新生儿血清PCT值,在诊断新生儿感染性疾病方面具有极强的临床价值,后经针对性抗感染治疗,能在一定程度上提高在该疾病的治愈率,同时也能避免过度使用抗生素,有助于减少耐药性。

Objective To analyze the diagnostic value of serum calcitonin in early neonatal infection.Methods From June 2015 to June 2017,98 cases of suspected infection-infected neonates in our hospital were selected as the study subjects.It was established as an infection group,and in the same period,a healthy group of 98 healthy newborns was taken as the health group,and the blood serum PCT and CPR were measured and the results were analyzed.Results Compared with healthy group,PCT and CRP value significantly higher infection group,the difference was statistically significant(P<0.05).CRP specificity,positive predictive value is higher than the PCT,sensitivity,negative predictive value and about index is lower than the PCT,data exist significant differences between groups,the difference was statistically significant(P<0.05).Conclusion In the early detection of neonatal serum PCT values,in the diagnosis of neonatal infectious diseases with a strong clinical value,after targeted anti-infection treatment,can improve the cure rate of the disease to a certain extent,but also can avoid excessive use of antibiotics,helps to reduce resistance.