磷酸肌酸对小儿心肌炎患者的临床疗效及其预后影响

The Effect of Creatine Phosphocreatine on the Clinical Effect and Prognosis of Children With Myocarditis

目的研究治疗小儿心肌炎采用磷酸肌酸的临床效果。方法选取我院2016年9月—2017年9月所收治的心肌炎患儿80例作为研究对象。根据患儿入院时间,将其分为研究组和参照组,每组各40例。参照组患儿给予心肌炎常规药物治疗,研究组患儿磷酸肌酸静脉滴注治疗,对比两组患儿治疗效果以及不良反应。结果研究组患儿治疗总有效率为97.5%,高于参照组患儿治疗总有效率75.0%,组间对比,差异具有统计学意义(P<0.05);研究组患儿治疗后不良反应发生率为7.5%,低于参照组患儿治疗后不良反应发生率27.5%,组间对比,差异具有统计学意义(P<0.05)。结论治疗小儿心肌炎采用磷酸肌酸具有显著临床效果,并且患儿不良反应相对较低,能够显著改善患儿各项临床症状。

Objective To study the clinical effect of creatine phosphocreatine in the treatment of children with myocarditis.Methods 80 cases of children with myocarditis treated in our hospital from September 2016 to September 2017 were selected as the research subjects.According to the time of hospitalization,the children were divided into the study group and the reference group,with 40 cases in each group.The children in the reference group were treated with conventional drugs for myocarditis.The children in the study group were treated with phosphocreatine infusion.The treatment effect and adverse reaction of the two groups were compared.Results The total effective rate of treatment in the study group was 97.5%.The total effective rate in the treatment group was 75.0%,and the difference between the groups was statistically significant(P<0.05).The incidence of adverse reactions in the study group was 7.5%after treatment.After treatment,the incidence of adverse reaction was 27.5%,and the difference between the groups was statistically significant(P<0.05).Conclusion Creatine phosphate has significant clinical effect in the treatment of pediatric myocarditis,and the adverse reactions of children are relatively low,which can significantly improve the clinical symptoms of children.